AP3S2 Antibodies

AND AP3S2 ELISA kits, AP3S2 Proteins

Many biological assays use antibodies to detect AP3S2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP3S2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP3S2 antibodies...

We validate the specificity of these antibodies to AP3S2 by testing them on tissues known to express AP3S2 positively and negatively. Browse below to find the AP3S2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP3S2 Infographic by Boster Bio

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AP3S2 (NM_005829) Human Over-expression Lysate

Human

$628
Cat # LS010239
100 µg

AP3S2 Overview

Facts about AP-3 complex subunit sigma-2.

AP3S2 3D structure. Source: alphafold

AP-3 complex subunit sigma-2 (AP3S2)

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures.

It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Gene Information

Human
Gene Name:	AP3S2
Uniprot:	P59780
Entrez:	10239

Family

Belongs to:

adaptor complexes small subunit family

Alternative Names

Adapter-related protein complex 3 sigma-2 subunit; adaptor complex sigma3B; adaptor-related protein complex 3, sigma 2 subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; AP3S3; clathrin-associated/assembly/adaptor protein, small 4, 22-kD; FLJ35955; sigma3b; sigma-3B-adaptin; Sigma3B-adaptin; Sigma-adaptin 3b

Molecular Weight

Mass (kDA):
22.017 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (89830599..89893994, complement)

Tissue Specificity

Present in all adult tissues examined.

Subcellular Localizations

Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Diseases

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Hypertensive Disease
Cardiovascular Diseases
Carotid Artery Diseases
Dental Plaque
Atherosclerosis

Insulin Sensitivity

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP3S2

References

PMID: 9118953 by Dell'Angelica E.C., et al. AP-3: an adaptor-like protein complex with ubiquitous expression.