Click image to see more details
Product Info Summary
| SKU: | M02267 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-AGXT Antibody
SKU/Catalog Number
M02267
Size
50 µl
Description
Boster Bio Anti-AGXT Antibody (Catalog # M02267). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-AGXT Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02267)
Host
Mouse
Contents
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Monoclonal
Clone Number
1739CT804.82.83.1
Isotype
IgG1,k
Immunogen
This AGXT antibody is generated from a mouse immunized with a recombinant protein between 188-375 amino acids from the human AGXT.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M02267 is reactive to AGXT in Human
Reconstitution
Calculated molecular weight
43010 Da
Background of AGXT
IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2- mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M02267 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000-1:2000
Validation Images & Assay Conditions
Click image to see more details
All lanes : Anti-AGXT Antibody at 1:1000-1:2000 dilution
Lane 1: HepG2 whole cell lysate
Lane 2: human liver lysate
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 43 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For AGXT (Source: Uniprot.org, NCBI)
Gene Name
AGXT
Full Name
Serine--pyruvate aminotransferase
Weight
43010 Da
Superfamily
class-V pyridoxal-phosphate-dependent aminotransferase family
Alternative Names
Serine--pyruvate aminotransferase, SPT, 2.6.1.51, Alanine--glyoxylate aminotransferase, AGT, 2.6.1.44, AGXT, AGT1, SPAT AGXT AGT, AGT11, PH1, SPAT, SPT, TLH6, AGXT alanine--glyoxylate and serine--pyruvate aminotransferase serine--pyruvate aminotransferase|L-alanine: glyoxylate aminotransferase 1|alanine-glyoxylate aminotransferase|hepatic peroxisomal alanine:glyoxylate aminotransferase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AGXT, check out the AGXT Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AGXT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-AGXT Antibody (M02267)
Loading publications
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-AGXT Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-AGXT Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
