Atlastin-1 Antibodies

AND ATL1 ELISA kits, Atlastin-1 Proteins

Many biological assays use antibodies to detect Atlastin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Atlastin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Atlastin-1 antibodies...

We validate the specificity of these antibodies to Atlastin-1 by testing them on tissues known to express ATL1 positively and negatively. Browse below to find the ATL1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: CALHM2

ATL1 Infographic by Boster Bio

All ATL1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Atlastin-1 ATL1 Antibody

Human, Mouse

IF, WB

$405
Cat # A01994
100ul

SPG3A (ATL1) (NM_015915) Human Recombinant Protein

$813
Cat # PROTQ8WXF7
20 µg

Anti-SPG3A/ATL1 Antibody Picoband®

Human

Flow Cytometry, IHC, WB

$370
Cat # A01994-1
100 μg/vial

SPG3A (ATL1) (NM_015915) Human Over-expression Lysate

Human

$628
Cat # LS051062
100 µg

Anti-ATL1 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A01994-2
100 µg/vial

ATL1 Overview

Facts about Atlastin-1.

ATL1 3D structure. Source: alphafold

Atlastin-1 (ATL1)

GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (PubMed:27619977).

May also regulate Golgi biogenesis. May regulate axonal development.

Gene Information

Human
Gene Name:	ATL1
Uniprot:	Q8WXF7
Entrez:	51062

Family

Belongs to:

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

AD-FSP; atlastin GTPase 1; atlastin1; atlastin-1; Brain-specific GTP-binding protein; EC 3.6.5.-; FSP1; GBP3; GBP-3; GTP-binding protein 3; Guanine nucleotide-binding protein 3; guanylate-binding protein 3; Spastic paraplegia 3 protein A; spastic paraplegia 3A (autosomal dominant); SPG3; SPG3AhGBP3

Molecular Weight

Mass (kDA):
63.544 kDA

Genomic Context


Human

Location:	14q22.1
Sequence:	14; NC_000014.9 (50533082..50633068)

Tissue Specificity

Expressed predominantly in the adult and fetal central nervous system. Measurable expression in all tissues examined, although expression in adult brain is at least 50-fold higher than in other tissues. Detected predominantly in pyramidal neurons in the cerebral cortex and the hippocampus of the brain. Expressed in upper and lower motor neurons (at protein level).

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon. Localizes to endoplasmic reticulum tubular network (PubMed:27619977).