RNA helicase aquarius Antibodies

AND AQR ELISA kits, RNA helicase aquarius Proteins

Many biological assays use antibodies to detect RNA helicase aquarius, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RNA helicase aquarius in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RNA helicase aquarius antibodies...

We validate the specificity of these antibodies to RNA helicase aquarius by testing them on tissues known to express AQR positively and negatively. Browse below to find the AQR antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AQR Infographic by Boster Bio

All AQR Products

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Anti-RNA helicase aquarius AQR Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03121
100ul

IBP160 (AQR) (NM_014691) Human Over-expression Lysate

Human

$960
Cat # LS009716
100 µg

AQR Overview

Facts about RNA helicase aquarius.

AQR 3D structure. Source: alphafold

RNA helicase aquarius (AQR)

Involved in pre-mRNA splicing as part of the spliceosome (PubMed:11991638, PubMed:25599396, PubMed:28502770, PubMed:28076346). Intron-binding spliceosomal protein necessary to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis (PubMed:16949364).

Plays a crucial role in position-dependent assembly of intron-encoded box C/D little snoRNP, splicing being required for snoRNP assembly (PubMed:16949364). May act by helping the folding of the snoRNA sequence.

Gene Information

Human
Gene Name:	AQR
Uniprot:	O60306
Entrez:	9716

Family

Belongs to:

CWF11 family

Alternative Names

AQR; aquarius homolog (mouse); FSAP164; Functional Spliceosome-Associated Protein 164; IBP160; Intron-Binding Protein Aquarius

Molecular Weight

Mass (kDA):
171.295 kDA

Genomic Context


Human

Location:	15q14
Sequence:	15; NC_000015.10 (34851782..34969742, complement)

Subcellular Localizations

Nucleus. Nucleus, nucleoplasm. Localizes to speckle-like regions of the nucleoplasm.

Diseases

Graft Vs Host Reaction
Neoplasms
Murine Hepatitis
Neoplasms, Experimental
Myeloid Leukemia, Chronic
Chimera Disorder
Hepatitis
Autoimmunity
Visna
Tick-borne Encephalitides, European
Tick-borne Encephalitis
Melanoma
Malaria, Falciparum

Sheep Diseases
Goat Diseases
Endoplasmic Reticulum Stress
Delayed Hypersensitivity
Pyotraumatic Dermatitis
Central European Encephalitis
Encephalitis

Interacting Proteins

ISY1
PPIE
XAB2
ZNF830

Pathways

Regeneration
Cell Activation
Tolerance Induction
Cell Migration
Aerotaxis
T Cell Activation
Immune Response
Hypersensitivity
Tumor Necrosis Factor Production

Social Behavior
Pathogenesis
Localization

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AQR

References

PMID: 16949364 by Hirose T., et al. A spliceosomal intron binding protein, IBP160, links Position- dependent assembly of intron-encoded box C/D snoRNP to pre-mRNA splicing.

PMID: 17981804 by Kuraoka I., et al. Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair.