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- Table of Contents
Facts about ATM interactor.
Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM.
Human | |
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Gene Name: | ATMIN |
Uniprot: | O43313 |
Entrez: | 23300 |
Belongs to: |
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No superfamily |
ASCIZ; ATM INteracting protein; ATM interactor; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; DKFZp779K1455; FLJ50270; FLJ61620; FLJ76795; KIAA0431; zinc finger protein 822; ZNF822
Mass (kDA):
88.348 kDA
Human | |
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Location: | 16q23.2 |
Sequence: | 16; NC_000016.10 (81035842..81047350) |
Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.
Nucleus. Nuclear, in discrete foci during G1 phase.
PMID: 15933716 by McNees C.J., et al. ASCIZ regulates lesion-specific Rad51 focus formation and apoptosis after methylating DNA damage.
PMID: 17525732 by Kanu N., et al. ATMIN defines an NBS1-independent pathway of ATM signalling.