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Apolipoprotein E Antibodies
AND APOE ELISA kits, Apolipoprotein E Proteins
Many biological assays use antibodies to detect Apolipoprotein E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Apolipoprotein E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Apolipoprotein E antibodies...
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APOE Infographic by Boster Bio
All APOE Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1455
96 wells/kit, with removable strips.
Cat # EK1455
96 wells/kit, with removable strips.
Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PB9986
100 μg/vial
Cat # PB9986
100 μg/vial
Anti-Apolipoprotein E/APOE Antibody Picoband®
1 Citations 17 Q&As
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # PB9327
100 μg/vial
Cat # PB9327
100 μg/vial
Anti-Apolipoprotein E APOE Monoclonal Antibody
2 Citations 15 Q&As
Human, Mouse
IP, IF, IHC, ICC, WB
$370
Cat # M00015
100 μl
Cat # M00015
100 μl
Human
ELISA
$500
Cat # EZ1455
For 5 plates, 96 wells each
Cat # EZ1455
For 5 plates, 96 wells each
Anti-Apolipoprotein E APOE Antibody
1 Citations
Human, Mouse
IP, IF, IHC, ICC, WB
$405
Cat # A00015-3
100ul
Cat # A00015-3
100ul
Anti-Apolipoprotein E ApoE Antibody
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$380
Cat # A00015-4
100ul
Cat # A00015-4
100ul
Human
ELISA
$499
Cat # FEK1455
96 wells/kit, with removable strips.
Cat # FEK1455
96 wells/kit, with removable strips.
APOE Overview
Facts about Apolipoprotein E.
Apolipoprotein E (APOE)
Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | APOE |
| Uniprot: | P02649 |
| Entrez: | 348 |
Family
| Belongs to: |
|---|
| apolipoprotein A1/A4/E family |
Alternative Names
APOE; Apo-E; Apolipoprotein E; apolipoprotein E3; late onset); MGC1571
Molecular Weight
Mass (kDA):
36.154 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.32 |
| Sequence: | 19; NC_000019.10 (44905796..44909395) |
Tissue Specificity
Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.
Subcellular Localizations
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins (PubMed:1911868, PubMed:8340399). Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans-dependent manner (PubMed:9488694). Lipidation induces the release from the extracellular matrix (PubMed:9488694).
Diseases
- Alzheimer's Disease
- Dementia
- Impaired Cognition
- Cognition Disorders
- Atherosclerosis
- Mild Cognitive Disorder
- Cardiovascular Diseases
- Diabetes Mellitus
- Vascular Diseases
- Cerebrovascular Accident
- Neurodegenerative Disorders
- Heart Diseases
- Depressive Disorder
Interacting Proteins
- APP
- CDC37
- ECSIT
- HP
- LDLR
- LRP1
- LRP8
- MAPT
- PDCD4
- ST13
Pathways
- Pathogenesis
- Aging
- Cognition
- Transport
- Lipid Transport
- Secretion
- Immune Response
- Cholesterol Efflux
- Inflammatory Response
- Cell Adhesion
- Localization
- Cholesterol Transport
- Menopause
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Glycosylation
- Methylation
- Nitration
Research Areas
- Alzheimers Research
- Apoptosis
- Cognition and Behavior
- Lipid and Metabolism
- Neurodegeneration
- Neuronal Cell Markers
- Neuroscience
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APOE
bosterbio.com/bosterbio-gene-info-cards/APOE
References
PMID: 6325438 by Zannis V.I., et al. Synthesis, intracellular processing, and signal peptide of human apolipoprotein E.
PMID: 6327682 by McLean J.W., et al. Human apolipoprotein E mRNA. cDNA cloning and nucleotide sequencing of a new variant.
2 Publications of Boster Apolipoprotein E Antibodies & ELISA Kits
- PubMed ID: 33061590, Xue Y,Huang S,Huang J,Li S,Zhang C,Zhou X.Identification of Apolipoprotein E as ...
- PubMed ID: 33205615, Kong Y, Zhao C, Huang Y, Liu Y, Liu S, Guo Y, Li M, Xu T, Zhao B, Wang J. Angiop...
*More publications can be found for each product on its corresponding product page