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- Table of Contents
Facts about Peroxisomal acyl-coenzyme A oxidase 2.
Human | |
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Gene Name: | ACOX2 |
Uniprot: | Q99424 |
Entrez: | 8309 |
Belongs to: |
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acyl-CoA oxidase family |
12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; 3-alpha; 7-alpha; acyl-CoA oxidase 2, branched chain; acyl-Coenzyme A oxidase 2, branched chain; BCOX; BRCACOXTHCA-CoA oxidase; BRCOX; EC 1.17.99.3; peroxisomal acyl-coenzyme A oxidase 2,3-alpha; peroxisomal branched chain acyl-CoA oxidase; THCCox; Trihydroxycoprostanoyl-CoA oxidase
Mass (kDA):
76.827 kDA
Human | |
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Location: | 3p14.3 |
Sequence: | 3; NC_000003.12 (58505136..58537196, complement) |
Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
Peroxisome.
PMID: 8943006 by Baumgart E., et al. Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger's syndrome.
PMID: 27647924 by Vilarinho S., et al. ACOX2 deficiency: A disorder of bile acid synthesis with transaminase elevation, liver fibrosis, ataxia, and cognitive impairment.