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- Table of Contents
Facts about Amphoterin-induced protein 1.
May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.
Human | |
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Gene Name: | AMIGO1 |
Uniprot: | Q86WK6 |
Entrez: | 57463 |
Belongs to: |
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immunoglobulin superfamily |
adhesion molecule with Ig-like domain 1; ali2; Alivin-2; AMIGO; AMIGO1; AMIGO-1; AMIGOamphoterin-induced protein 1; amphoterin-induced gene and ORF; KIAA1163
Mass (kDA):
55.239 kDA
Human | |
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Location: | 1p13.3 |
Sequence: | 1; NC_000001.11 (109504178..109509742, complement) |
Cell membrane; Single-pass type I membrane protein. Perikaryon. Cell projection, dendrite. Cell projection, axon. Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal and cortical neurons. Associated with axons of neuronal cells.
PMID: 12629050 by Kuja-Panula J., et al. AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats.