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- Table of Contents
8 Citations 17 Q&As
8 Citations 16 Q&As
Facts about Allograft inflammatory factor 1.
Binds calcium. Plays a role in RAC signaling and in phagocytosis.
Human | |
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Gene Name: | AIF1 |
Uniprot: | P55008 |
Entrez: | 199 |
Belongs to: |
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No superfamily |
AIF1; AIF-1; AIF-1IRT1; allograft inflammatory factor 1; G1; IBA1; IBA1Em:AF129756.17; IbaI; interferon gamma responsive transcript; Ionized calcium-binding adapter molecule 1; IRT1; IRT-1; Protein G1
Mass (kDA):
16.703 kDA
Human | |
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Location: | 6p21.33 |
Sequence: | 6; NC_000006.12 (31615212..31617015) |
Detected in T-lymphocytes and peripheral blood mononuclear cells.
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, phagocytic cup. Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
PMID: 8081366 by Albertella M.R., et al. Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins.
PMID: 7590964 by Holzinger I., et al. Cloning and genomic characterization of LST1: a new gene in the human TNF region.
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