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- Table of Contents
Facts about Rho GTPase-activating protein 22.
Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating action of this endothelin-1 (EDN1) promoter (By similarity).
Human | |
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Gene Name: | ARHGAP22 |
Uniprot: | Q7Z5H3 |
Entrez: | 58504 |
Belongs to: |
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No superfamily |
Rho GTPase activating protein 22; rho GTPase-activating protein 22; RhoGAP2; Rho-type GTPase-activating protein 22
Mass (kDA):
76.779 kDA
Human | |
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Location: | 10q11.22-q11.23 |
Sequence: | 10; NC_000010.11 (48429831..48656265, complement) |
Cytoplasm. Nucleus. Mainly cytoplasmic. Some fraction is nuclear (By similarity).
PMID: 15254788 by Katoh M., et al. Identification and characterization of ARHGAP24 and ARHGAP25 genes in silico.