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ACE Antibodies
AND ACE ELISA kits, ACE Proteins
Many biological assays use antibodies to detect ACE, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACE in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACE antibodies...
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ACE Infographic by Boster Bio
All ACE Products
Product
Figures
Specificity
Applications
Price
Human ACE/Cd143 ELISA Kit PicoKine®
10 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0557
96 wells/kit, with removable strips.
Cat # EK0557
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0558
96 wells/kit, with removable strips.
Cat # EK0558
96 wells/kit, with removable strips.
Anti-Angiotensin Converting Enzyme 1/ACE Antibody Picoband®
1 Citations 16 Q&As
Human
IHC, WB
$370
Cat # PA2196-1
100 μg/vial
Cat # PA2196-1
100 μg/vial
Anti-Angiotensin Converting Enzyme 1/ACE Antibody Picoband®
2 Citations 15 Q&As
Human, Mouse
WB
$370
Cat # PA2196-2
100 μg/vial
Cat # PA2196-2
100 μg/vial
Anti-Angiotensin Converting Enzyme 1/ACE Antibody Picoband®
4 Citations 5 Q&As
Human, Mouse, Rat
IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9124
100 μg/vial
Cat # PB9124
100 μg/vial
Anti-Angiotensin Converting Enzyme 1/Ace Antibody Picoband®
2 Citations 15 Q&As
Mouse, Rat
WB
$370
Cat # A00251
100 μg/vial
Cat # A00251
100 μg/vial
Anti-ACE1 Monoclonal Antibody
1 Citations 3 Q&As
Human, Mouse
Flow Cytometry, IHC, WB
$370
Cat # M00251
100 μl
Cat # M00251
100 μl
Human, Mouse
Flow Cytometry, IHC, WB
$405
Cat # A00251-1
100ul
Cat # A00251-1
100ul
Human
IHC, WB
$523
Cat # M00251-1
100 µl
Cat # M00251-1
100 µl
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00251-3
100 μg/vial
Cat # A00251-3
100 μg/vial
Human
ELISA
$499
Cat # FEK0557
96 wells/kit, with removable strips.
Cat # FEK0557
96 wells/kit, with removable strips.
ACE Overview
Facts about Angiotensin-converting enzyme.
Angiotensin-converting enzyme (ACE)
Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator.
Has also a glycosidase activity that releases GPI-anchored proteins from the membrane by cleaving the mannose linkage from the GPI moiety. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ACE |
| Uniprot: | P12821 |
| Entrez: | 1636 |
Family
| Belongs to: |
|---|
| peptidase M2 family |
Alternative Names
ACE; ACE1angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; carboxycathepsin; CD143 antigen; CD143; DCP; DCP1; DCP1angiotensin-converting enzyme; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase I; EC 3.2.1.-; EC 3.4.15.1; Kininase II; MGC26566; MVCD3; peptidase P; testicular ECA
Molecular Weight
Mass (kDA):
149.715 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q23.3 |
| Sequence: | 17; NC_000017.11 (63477061..63498373) |
Tissue Specificity
Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.
Subcellular Localizations
[Angiotensin-converting enzyme, soluble form]: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm. Detected in both cell membrane and cytoplasm in neurons.
Diseases
- Hypertensive Disease
- Heart Failure
- Diabetes Mellitus
- Kidney Diseases
- Myocardial Infarction
- Infarction
- Cardiovascular Diseases
- Hypertrophy
- Heart Diseases
- Diabetes Mellitus, Non-insulin-dependent
- Kidney Failure, Chronic
- Diabetic Nephropathy
- Kidney Failure
Pathways
- Excretion
- Pathogenesis
- Glomerular Filtration
- Vasoconstriction
- Secretion
- Vasodilation
- Localization
- Transport
- Aging
- Reflex
- Cell Proliferation
- Natriuresis
- Coagulation
PTMs
- Cleavage
- Nitration
- Phosphorylation
- Glycosylation
- Oxidation
- Reduction
- Acetylation
- Carboxylation
- Biotinylation
- Iodination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACE
bosterbio.com/bosterbio-gene-info-cards/ACE
References
PMID: 2849100 by Soubrier F., et al. Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.
PMID: 2547653 by Lattion A.L., et al. The testicular transcript of the angiotensin I-converting enzyme encodes for the ancestral, non-duplicated form of the enzyme.
14 Publications of Boster ACE Antibodies & ELISA Kits
- PubMed ID: 10.3892/mmr.2017.6201, Low concentrations of bilirubin inhibit activation of hepatic stellate cells in�...
- PubMed ID: 10.1371/journal.pone.0084274, Autonomic Cardiovascular Responses in Acclimatized Lowlanders on Prolonged Stay ...
- PubMed ID: 10.1177/1934578X1801300115, Malvidin and its Glycosides from Vaccinium ashei Improve Endothelial Function by...
- PubMed ID: 10.1155/2018/3846029, Protective Role of Antioxidant Huskless Barley Extracts on TNF-α-Induced Endoth...
- PubMed ID: 10.1016/j.resp.2018.04.002, Differential responses of autonomic function in sea level residents, acclimatize...
- PubMed ID: 10.1016/j.apjtm.2017.03.016, Combination of serum tumor markers dickkopf-1, DCP and AFP for the diagnosis of ...
- PubMed ID: 10.1007/s00198-014-2992-y, Local renin-angiotensin system is associated with bone mineral density of glucoc...
- PubMed ID: 10.1002/ppul.23886, Angiotensin‐converting enzyme insertion/deletion gene polymorphism in Egyptian...
- PubMed ID: 29969996, Telmisartan protects chronic intermittent hypoxic mice via modulating cardiac re...
- PubMed ID: 28765966, Aliskiren has chondroprotective efficacy in a rat model of osteoarthritis throug...
- PubMed ID: 29861828, Protective Role of Antioxidant Huskless Barley Extracts on TNF-?-Induced Endothe...
- PubMed ID: 29201746, Role of Renin?Angiotensin-converting Enzyme Level and ACE Gene Polymorphism in P...
- PubMed ID: 25926900, Angiotensin(1-7) and ACE2, ?The Hot Spots? of Renin-Angiotensin System, Detected...
- PubMed ID: 24404157, Autonomic Cardiovascular Responses in Acclimatized Lowlanders on Prolonged Stay ...
*More publications can be found for each product on its corresponding product page