ACP4 Antibodies

AND ACP4 ELISA kits, ACP4 Proteins

Many biological assays use antibodies to detect ACP4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACP4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACP4 antibodies...

We validate the specificity of these antibodies to ACP4 by testing them on tissues known to express ACP4 positively and negatively. Browse below to find the ACP4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ACP4 Infographic by Boster Bio

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ACP4 (NM_033068) Human Over-expression Lysate

Human

$960
Cat # LS093650
100 µg

ACP4 Overview

Facts about Testicular acid phosphatase.

ACP4 3D structure. Source: alphafold

Testicular acid phosphatase (ACP4)

May dephosphorylate receptor tyrosine-protein kinase ERBB4 and inhibits its ligand-induced proteolytic cleavage (PubMed:15219672). May play a role in odontogenesis (PubMed:27843125).

Gene Information

Human
Gene Name:	ACP4
Uniprot:	Q9BZG2
Entrez:	93650

Family

Belongs to:

histidine acid phosphatase family

Alternative Names

Testicular acid phosphatase

Molecular Weight

Mass (kDA):
46.09 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (50790415..50795219)

Tissue Specificity

Expressed mainly in the testis. Also expressed in the brain where they are enriched at the postsynaptic sites. Expressed at lower levels in the trachea, prostate, bone marrow, spinal cord, colon, fetal brain, heart, thymus, fetal liver, spleen, leukocytes, ovary, small intestine, pancreas and skeletal muscle. Expression is significantly lower in testicular cancer tissues than in normal testicular tissues. Isoform 3 is expressed in the testis, trachea, prostate and bone marrow.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Amelogenesis imperfecta 1J (AI1J)

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACP4

References

PMID: 11414767 by Yousef G.M., et al. Molecular cloning of a novel human acid phosphatase gene (ACPT) that is highly expressed in the testis.

PMID: 15219672 by Fleisig H., et al. Regulation of ErbB4 phosphorylation and cleavage by a novel histidine acid phosphatase.