Product Info Summary
SKU: | A05168 |
---|---|
Size: | 100 µl |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-ASPSCR1/Tug Antibody
SKU/Catalog Number
A05168
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-ASPSCR1/Tug Antibody (Catalog # A05168). Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ASPSCR1/Tug Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05168)
Host
Rabbit
Contents
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Peptide sequence around aa.303 ~307(P-Q-Q-E-Q) derived from Human ASPSCR1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A05168 is reactive to ASPSCR1 in Human
Reconstitution
Observed Molecular Weight
111 kDa
Calculated molecular weight
60183 MW
Background of TUG
Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.
Ladanyi, M. et al. (2001) Oncogene 20, 48-57.
Bogan, J.S. et al. (2003) Nature 425, 727-33.
Yu, C. et al. (2007) J Biol Chem 282, 7710-22.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05168 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Predicted MW: 70-75kd
Western blotting: 1:500~1:1000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from HL60 cells using ASPSCR1 antibody A05168.
Protein Target Info & Infographic
Gene/Protein Information For ASPSCR1 (Source: Uniprot.org, NCBI)
Gene Name
ASPSCR1
Full Name
Tether containing UBX domain for GLUT4
Weight
60183 MW
Alternative Names
Tether containing UBX domain for GLUT4;Alveolar soft part sarcoma chromosomal region candidate gene 1 protein;Alveolar soft part sarcoma locus;Renal papillary cell carcinoma protein 17;UBX domain-containing protein 9;ASPSCR1;ASPL, RCC17, TUG, UBXD9, UBXN9; Aspscr1|1190006K01Rik, A, AS, ASPC, ASPCR1, ASPL, ASPS, RCC1, RCC17, TUG|alveolar soft part sarcoma chromosome region, candidate 1 (human)|tether containing UBX domain for GLUT4|alveolar soft part sarcoma chromosomal region candidate gene 1 protein homolog|tether, containing a UBX domain, for GLUT4
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ASPSCR1, check out the ASPSCR1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ASPSCR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ASPSCR1/Tug Antibody (A05168)
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No publications found for A05168
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