ADCYAP1 Antibodies

AND ADCYAP1 ELISA kits, ADCYAP1 Proteins

Many biological assays use antibodies to detect ADCYAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADCYAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADCYAP1 antibodies...

We validate the specificity of these antibodies to ADCYAP1 by testing them on tissues known to express ADCYAP1 positively and negatively. Browse below to find the ADCYAP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADCYAP1 Infographic by Boster Bio

All ADCYAP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PACA ADCYAP1 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A01711
100ul

PACAP (ADCYAP1) (NM_001117) Human Recombinant Protein

$1062
Cat # PROTP18509
20 µg

Anti-PACAP-38/ADCYAP1 Antibody Picoband®

Human

Flow Cytometry, IHC, WB

$370
Cat # A01711-1
100 μg/vial

PACAP (ADCYAP1) (NM_001099733) Human Over-expression Lysate

Human

$628
Cat # LS000116
100 µg

Anti-PACAP38 Reference Antibody (Lilly patent anti-PACAP)

Cynomolgus monkey, Human, Rat

ELISA, Flow Cytometry, FTA

$349
Cat # M01711
100 &mug

ADCYAP1 Overview

Facts about Pituitary adenylate cyclase-activating polypeptide.

ADCYAP1 3D structure. Source: alphafold

Pituitary adenylate cyclase-activating polypeptide (ADCYAP1)

Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.

In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity).

Gene Information

Human
Gene Name:	ADCYAP1
Uniprot:	P18509
Entrez:	116

Family

Belongs to:

glucagon family

Alternative Names

ADCYAP1; adenylate cyclase activating polypeptide 1 (pituitary); PACAP; PACAPMGC126852; pituitary adenylate cyclase-activating polypeptide

Molecular Weight

Mass (kDA):
18.835 kDA

Genomic Context


Human

Location:	18p11.32
Sequence:	18; NC_000018.10 (904384..912172)

Subcellular Localizations

Secreted.

Diseases

Pituitary Diseases
Nervousness
Neoplasms
Inflammation
Disease Of Adrenal Medulla
Observation Of Neuromuscular Block
Malignant Neoplasms
Ischemia
Neuroblastoma
Pertussis
Pheochromocytoma
Cholera
Diabetes Mellitus

Pituitary Neoplasms
Autoimmune Reaction
Autoimmune Diseases
Pain
Carcinoma
Adenoma
Brain Injuries

Interacting Proteins

Pathways

Secretion
Localization
Cell Proliferation
Cell Death
Insulin Secretion
Innervation
Catecholamine Secretion
Transport
Acid Secretion
Hormone Secretion
Pathogenesis
Cell Growth
Immune Response

Neurogenesis
Ovulation
Neuroprotection
Cell Differentiation
Inflammatory Response
Gastric Acid Secretion
Vasodilation

PTMs

Phosphorylation
Amidation
Cleavage
Biotinylation
Reduction

Methylation
Ribosylation
Sulphation
Oxidation
Iodination

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADCYAP1

References

PMID: 1739432 by Ohkubo S., et al. Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide.

PMID: 1730060 by Hosoya M., et al. Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene.