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- Table of Contents
Facts about Acidic leucine-rich nuclear phosphoprotein 32 family member A.
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Human | |
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Gene Name: | ANP32A |
Uniprot: | P39687 |
Entrez: | 8125 |
Belongs to: |
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ANP32 family |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic nuclear phosphoprotein pp32; cerebellar leucine rich acidic nuclear protein; I1PP2A; inhibitor-1 of protein phosphatase-2A; LANPPutative HLA-DR-associated protein I; Leucine-rich acidic nuclear protein; MAPMC15orf1; mapmodulin; PHAP1MGC150373; PHAPIMGC119787; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; PP32; putative human HLA class II associated protein I
Mass (kDA):
28.585 kDA
Human | |
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Location: | 15q23 |
Sequence: | 15; NC_000015.10 (68778535..68820895, complement) |
Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala.
Nucleus. Cytoplasm. Endoplasmic reticulum. Translocates to the cytoplasm during the process of neuritogenesis (By similarity). Shuttles between nucleus and cytoplasm.
PMID: 8192856 by Vaesen M., et al. Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII.
PMID: 8679524 by Li M., et al. Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A.