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- Table of Contents
Facts about ADM.
In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion.
Human | |
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Gene Name: | ADM |
Uniprot: | P35318 |
Entrez: | 133 |
Belongs to: |
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adrenomedullin family |
ADM; Adrenomedullin; AMpreproadrenomedullin
Mass (kDA):
20.42 kDA
Human | |
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Location: | 11p15.4 |
Sequence: | 11; NC_000011.10 (10305073..10307397) |
Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.
Secreted.
PMID: 7688224 by Kitamura K., et al. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin.
PMID: 8074714 by Ishimitsu T., et al. Genomic structure of human adrenomedullin gene.
*More publications can be found for each product on its corresponding product page