This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
A-kinase anchor protein 9 Antibodies
AND AKAP9 ELISA kits, A-kinase anchor protein 9 Proteins
Many biological assays use antibodies to detect A-kinase anchor protein 9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with A-kinase anchor protein 9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop A-kinase anchor protein 9 antibodies...
Previous: CCN4
Next: FAM13A
AKAP9 Infographic by Boster Bio
All AKAP9 Products
Product
Figures
Specificity
Applications
Price
AKAP9 Overview
Facts about A-kinase anchor protein 9.
A-kinase anchor protein 9 (AKAP9)
Scaffolding protein which assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus (PubMed:10202149, PubMed:15047863).
Required for microtubule nucleation in the cis-side of the Golgi apparatus (PubMed:15047863, PubMed:19242490). Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase (PubMed:25657325).
Gene Information
| Human | |
|---|---|
| Gene Name: | AKAP9 |
| Uniprot: | Q99996 |
| Entrez: | 10142 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
A kinase (PRKA) anchor protein (yotiao) 9; AKAP 350; AKAP 450; AKAP350A-kinase anchor protein 450 kDa; AKAP450A-kinase anchor protein 350 kDa; AKAP-9; Centrosome- and Golgi-localized PKN-associated protein; CG-NAPAKAP 120-like protein; hgAKAP 350; HYPERION; KIAA0803A-kinase anchor protein 9; MU-RMS-40.16A; PRKA9AKAP9-BRAF fusion protein; Protein hyperion; protein kinase A anchoring protein 9; Protein kinase A-anchoring protein 9; Protein yotiao; YOTIAOkinase N-associated protein
Molecular Weight
Mass (kDA):
452.987 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.2 |
| Sequence: | 7; NC_000007.14 (91940862..92112908) |
Tissue Specificity
Widely expressed (PubMed:10202149). Isoform 4: Highly expressed in skeletal muscle and in pancreas (PubMed:9482789).
Subcellular Localizations
Golgi apparatus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic in parietal cells (PubMed:9915845). Recruited to the Golgi apparatus by GM130/GOLGA2 (PubMed:25657325). Localization at the centrosome versus Golgi apparatus may be cell line-dependent. In SKBr3 and HEK293F cells, exclusively located at the centrosome (PubMed:29162697). In HeLa, MDA-MB231 and RPE-1 cells, detected at the Golgi apparatus (PubMed:25217626, PubMed:29162697). In SK-BR-3 cells, recruited to the centrosome in the presence of CDK5RAP2 (PubMed:29162697).
Diseases
- Malignant Neoplasms
- Long Qt Syndrome
- Cardiac Arrhythmia
- Nervousness
- Carcinoma
- Neoplasms
- Thyroid Neoplasm
- Carcinoma, Papillary
- Sudden Cardiac Death
- Cardiac Death
- Tissue Adhesions
- Malignant Neoplasm Of Thyroid
Interacting Proteins
- Adcy2
- BLZF1
- C1orf94
- GOLGA2
- HNRNPM
- IKZF3
- KDM1A
- MAGEA6
- MAGED1
- PRDM14
Pathways
- Localization
- Cell Cycle
- Microtubule Nucleation
- Interphase
- Cell Migration
- Mitosis
- Cytokinesis
- Secretion
- Cell Adhesion
- Cell Proliferation
- Telophase
- Transport
- Cell Activation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKAP9
bosterbio.com/bosterbio-gene-info-cards/AKAP9
References
PMID: 9482789 by Lin J.W., et al. Yotiao, a novel protein of neuromuscular junction and brain that interacts with specific splice variants of NMDA receptor subunit NR1.
PMID: 10202149 by Witczak O., et al. Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450.