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Aquaporin-4 Antibodies
AND AQP4 ELISA kits, Aquaporin-4 Proteins
Many biological assays use antibodies to detect Aquaporin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Aquaporin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Aquaporin-4 antibodies...
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AQP4 Infographic by Boster Bio
All AQP4 Products
Product
Figures
Specificity
Applications
Price
Anti-Aquaporin 4/AQP4 Antibody Picoband®
9 Citations 18 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PB9475
100 μg/vial
Cat # PB9475
100 μg/vial
Anti-Aquaporin 4/AQP4 Antibody Picoband®
5 Citations 16 Q&As
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1937
100 μg/vial
Cat # PA1937
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$380
Cat # M01049
100ul
Cat # M01049
100ul
Anti-Aquaporin 4/AQP4 Antibody Picoband®
3 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01049
100 μg/vial
Cat # A01049
100 μg/vial
AQP4 Overview
Facts about Aquaporin-4.
Aquaporin-4 (AQP4)
Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | AQP4 |
| Uniprot: | P55087 |
| Entrez: | 361 |
Family
| Belongs to: |
|---|
| MIP/aquaporin (TC 1.A.8) family |
Alternative Names
aquaporin 4; MGC22454
Molecular Weight
Mass (kDA):
34.83 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q11.2 |
| Sequence: | 18; NC_000018.10 (26852038..26865803, complement) |
Tissue Specificity
Brain - muscle >> heart, kidney, lung, and trachea.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection. Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane. Detected on brain astrocyte processes and astrocyte endfeet close to capillaries.
Diseases
- Edema
- Neuromyelitis Optica
- Brain Edema
- Nervousness
- Multiple Sclerosis
- Sclerosis
- Myelitis
- Optic Neuritis
- Neuritis
- Demyelinating Diseases
- Brain Injuries
- Autoimmune Reaction
Pathways
- Transport
- Water Transport
- Localization
- Pathogenesis
- Water Homeostasis
- Secretion
- Fluid Transport
- Ion Homeostasis
- Cell Migration
- Cell Death
- Angiogenesis
- Cellular Localization
- Complement Activation
PTMs
- Phosphorylation
- Glycosylation
- Biotinylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AQP4
bosterbio.com/bosterbio-gene-info-cards/AQP4
References
PMID: 7559426 by Yang B., et al. cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units.
PMID: 8601457 by Misaka T., et al. A water channel closely related to rat brain aquaporin 4 is expressed in acid- and pepsinogen-secretory cells of human stomach.
12 Publications of Boster Aquaporin-4 Antibodies & ELISA Kits
- PubMed ID: PMID:24995117, Ulinastatin attenuates cerebral ischemia-reperfusion injury in rats
- PubMed ID: 10.3171/2008.4.JNS17512, Brain edema after intracerebral hemorrhage in rats: the role of iron overload an...
- PubMed ID: 10.1096/fj.202100673R, Group 2 innate lymphoid cells suppress the pathology of neuromyelitis optica spe...
- PubMed ID: 10.1080/09291016.2021.2007329, Expression of AQP1, AQP3, AQP4 and AQP5 in upper respiratory tract of buffaloes ...
- PubMed ID: 10.1055/s-0034-1368584, Neuroprotective effects of total steroid saponins on cerebral ischemia injuries ...
- PubMed ID: 10.1002/jcb.26176, Down‐Regulation of AQP4 Expression via p38 MAPK Signaling in Temozolomide‐In...
- PubMed ID: 33484756, Song T,Chen W,Chen X,Zhang H,Zou Y,Wu H,Lin F,Ren L,Kang Y,Lei H.Repeated fluoxe...
- PubMed ID: 29351212, Changes in the Expression of AQP4 and AQP9 in the Hippocampus Following Eclampsi...
- PubMed ID: 26261083, Expression pattern of aquaporins in patients with primary nephrotic syndrome wit...
- PubMed ID: 24963614, Neuroprotective effects of total steroid saponins on cerebral ischemia injuries ...
- PubMed ID: 29445328, Anzabi M, Ardalan M, Iversen NK, Rafati AH, Hansen B, ?stergaard L. Front Cell N...
- PubMed ID: 24995117, Chen Hm, Huang Hs, Ruan L, He Yb, Li Xj. Int J Clin Exp Med. 2014 May 15;7(5):14...
*More publications can be found for each product on its corresponding product page