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Abl interactor 1 Antibodies
AND ABI1 ELISA kits, Abl interactor 1 Proteins
Many biological assays use antibodies to detect Abl interactor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Abl interactor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Abl interactor 1 antibodies...
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ABI1 Infographic by Boster Bio
All ABI1 Products
Product
Figures
Specificity
Applications
Price
Anti-SSH3BP1/ABI1 Antibody Picoband®
1 Citations 6 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9416
100 μg/vial
Cat # PB9416
100 μg/vial
Anti-SSH3BP1/ABI1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA1001
100 μg/vial
Cat # PA1001
100 μg/vial
ABI1 Overview
Facts about Abl interactor 1.
Abl interactor 1 (ABI1)
May act in negative regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. May play a role in regulation of EGF-induced Erk pathway activation.
Involved in cytoskeletal reorganization and EGFR signaling. Together with EPS8 participates in transduction of signals from Ras to Rac.
Gene Information
| Human | |
|---|---|
| Gene Name: | ABI1 |
| Uniprot: | Q8IZP0 |
| Entrez: | 10006 |
Family
| Belongs to: |
|---|
| ABI family |
Alternative Names
Abelson interactor 1; ABI1; ABI-1; abl interactor 1; Abl-binding protein 4; ABLBP4; abl-interactor 1; Abl-interactor protein 1 long; E3B1; eps8 binding protein; Eps8 SH3 domain-binding protein; Eps8-binding protein; interactor protein AblBP4; nap1 binding protein; Nap1-binding protein; NAP1BP; spectrin SH3 domain binding protein 1; Spectrin SH3 domain-binding protein 1; SSH3BP; SSH3BP1
Molecular Weight
Mass (kDA):
55.081 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10p12.1 |
| Sequence: | 10; NC_000010.11 (26746596..26861087, complement) |
Tissue Specificity
Widely expressed, with highest expression in brain.
Subcellular Localizations
Cytoplasm. Nucleus. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, growth cone. Cell junction, synapse, postsynaptic density. Cytoplasm, cytoskeleton. Localized to protruding lamellipodia and filopodia tips. Also localized to neuronal growth cones and synaptosomes. May shuttle from the postsynaptic densities to the nucleus (By similarity).
Diseases
- Physiological Stress
- Neoplasms
- Malignant Neoplasms
- Leukemia
- Tissue Adhesions
- Cell Invasion
- Dehydration
- Stress, Water
- Carcinoma
- Protrusion
- Wiskott-aldrich Syndrome
- Neoplasm Metastasis
- Plant Diseases
Interacting Proteins
- ABL1
- ABL2
- CACNA1A
- CBL
- Eps8
- ITGA4
- NCF1
- NCKAP1
- PIK3R1
- Pik3r1
Pathways
- Germination
- Stomatal Closure
- Seed Germination
- Localization
- Cell Migration
- Hypersensitivity
- Cell Proliferation
- Rna Interference
- Transport
- Seed Development
- Drought Tolerance
- Cell Growth
- Seed Maturation
PTMs
- Phosphorylation
- Dephosphorylation
- Nitration
- Farnesylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABI1
bosterbio.com/bosterbio-gene-info-cards/ABI1
References
PMID: 9010225 by Biesova Z., et al. Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth.
PMID: 9593709 by Ziemnicka-Kotula D., et al. Identification of a candidate human spectrin Src homology 3 domain- binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton.
1 Publications of Boster Abl interactor 1 Antibodies & ELISA Kits
- PubMed ID: 19554484, Cui M, Yu W, Dong J, Chen J, Zhang X, Liu Y. Med Oncol. 2010 Sep;27(3):632-9. Do...
*More publications can be found for each product on its corresponding product page