AGL Antibodies

AND AGL ELISA kits, AGL Proteins

Many biological assays use antibodies to detect AGL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AGL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AGL antibodies...

We validate the specificity of these antibodies to AGL by testing them on tissues known to express AGL positively and negatively. Browse below to find the AGL antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AGL Infographic by Boster Bio

All AGL Products

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Figures

Specificity

Applications

Price

AGL (NM_000643) Human Recombinant Protein

$1249
Cat # PROTP35573
20 µg

Anti-AGL Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02555
100 μl/vial

Anti-AGL Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02555
100 µg/vial

AGL Overview

Facts about Glycogen debranching enzyme.

AGL 3D structure. Source: alphafold

Glycogen debranching enzyme (AGL)

Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4- alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6- glucosidase in Insulin degradation. .

Gene Information

Human
Gene Name:	AGL
Uniprot:	P35573
Entrez:	178

Family

Belongs to:

glycogen debranching enzyme family

Alternative Names

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase; GDEamylo-1, 6-glucosidase, 4-alpha-glucanotransferase; Glycogen debrancher; glycogen debranching enzyme

Molecular Weight

Mass (kDA):
174.764 kDA

Genomic Context


Human

Location:	1p21.2
Sequence:	1; NC_000001.11 (99850077..99924023)

Tissue Specificity

Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle.

Subcellular Localizations

Cytoplasm. Under glycogenolytic conditions localizes to the nucleus.

Diseases

Glycogen Storage Disease Type Iii
Glycogen Storage Disease
Storage Disease
Hypoglycemia
Malignant Neoplasms
Leukemia, Myelocytic, Acute
Hepatomegaly
Leukemia
Cardiomyopathies
Myopathy
Lymphoma
Myeloid Leukemia
Hyperlipidemia

Myeloid Leukemia, Chronic
Chronic Lymphocytic Leukemia
Dwarfism
Pancreatitis
Lymphoid Leukemia
Pancreatic Neoplasm
B-cell Lymphomas

Pathways

Transport
Glycosylation
Pathogenesis
Flower Development
Excretion
Flight
Seed Development
Translation
Associative Learning
Localization
Maternal Behavior
Cellularization
Cell Growth

Endosperm Development
Secretion
Gene Silencing
Fertilization
Aging
Oxidative Phosphorylation
Sporulation

PTMs

Glycosylation
Phosphorylation
Methylation
Ubiquitination

Biotinylation
Reduction
Decarboxylation
Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AGL

References

PMID: 1374391 by Yang B.-Z., et al. Molecular cloning and nucleotide sequence of cDNA encoding human muscle glycogen debranching enzyme.

PMID: 8954797 by Bao Y., et al. Human glycogen debranching enzyme gene (AGL): complete structural organization and characterization of the 5' flanking region.