Product Info Summary
SKU: | A04010 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-ADRM1 Antibody
SKU/Catalog Number
A04010
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ADRM1 Antibody (Catalog # A04010). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ADRM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-ADRM1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04010)
Host
Rabbit
Contents
ADRM1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ADRM1 antibody was raised against a 19 amino acid peptide near the center of human ADRM1. The immunogen is located within amino acids 210 - 260 of ADRM1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ADRM1 antibody is human, mouse and rat reactive. At least two isoforms of ADRM1 are know to exist; this antibody will detect both isoforms.
Reactive Species
A04010 is reactive to ADRM1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
42153 MW
Background of ADRM1
The adhesion-regulating molecule 1 (ADRM1) is thought to be involved in protein recruitment and cell adhesion and functions as a proteasomal ubiquitin receptor (1). ADRM1 promotes the activity of UCH-L5 and plays a role in lymphocyte homing. The carboxy-terminal domain of mammalian ADRM1 serves to bind and enhance the isopeptidase activity of UCHL5/UCH37, perhaps serving as a mechanism to accelerate ubiquitin chain disassembly (2,3). ADRM1 expression is induced by IFN-gamma in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis (4,5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04010 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ADRM1 antibody can be used for detection of ADRM1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ADRM1 in EL cell lysate with ADRM1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Click image to see more details
Immunohistochemistry of ADRM1 in human spleen tissue with ADRM1 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ADRM1 (Source: Uniprot.org, NCBI)
Gene Name
ADRM1
Full Name
Proteasomal ubiquitin receptor ADRM1
Weight
42153 MW
Superfamily
ADRM1 family
Alternative Names
Adhesion regulating molecule 1, ARM1, Gp110, hRpn13, Proteasomal ubiquitin receptor ADRM1, Proteasome regulatory particle non-ATPase 13, Rpn13 ADRM1 ARM-1, ARM1, GP110, PSMD16 ADRM1 26S proteasome ubiquitin receptor proteasomal ubiquitin receptor ADRM1|110 kDa cell membrane glycoprotein|M(r) 110,000 surface |adhesion regulating molecule 1|proteasome regulatory particle non-ATPase 13|proteasome ubiquitin receptor|rpn13 homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ADRM1, check out the ADRM1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ADRM1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ADRM1 Antibody (A04010)
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