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- Table of Contents
Facts about Arachidonate 5-lipoxygenase.
Human | |
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Gene Name: | ALOX5 |
Uniprot: | P09917 |
Entrez: | 240 |
Belongs to: |
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lipoxygenase family |
5Lipoxygenase; 5-Lipoxygenase; 5-LO; 5-LOX; 5LPG; ALOX5; arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; EC 1.13.11; EC 1.13.11.34; leukotriene A4 synthase; LOG5; LOX5A; MGC163204
Mass (kDA):
77.983 kDA
Human | |
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Location: | 10q11.21 |
Sequence: | 10; NC_000010.11 (45374166..45446121) |
Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.
PMID: 3422434 by Dixon R.A.F., et al. Cloning of the cDNA for human 5-lipoxygenase.
PMID: 2829172 by Matsumoto T., et al. Molecular cloning and amino acid sequence of human 5-lipoxygenase.