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- Table of Contents
Facts about Artemin.
Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a significant part of the gut-associated lymphoid tissue. .
Human | |
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Gene Name: | ARTN |
Uniprot: | Q5T4W7 |
Entrez: | 9048 |
Belongs to: |
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TGF-beta family |
Artemin; ARTN; Enovin; EVN; EVNneurotrophic factor; NBN; Neublastin
Mass (kDA):
22.878 kDA
Human | |
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Location: | 1p34.1 |
Sequence: | 1; NC_000001.11 (43933320..43937240) |
Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
Secreted.
PMID: 9883723 by Baloh R.H., et al. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex.
PMID: 10583383 by Masure S., et al. Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. Existence and tissue-specific expression of different splice variants.