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- Table of Contents
Facts about Acetoacetyl-CoA synthetase.
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Rat | |
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Gene Name: | Aacs |
Uniprot: | Q9JMI1 |
Entrez: | 65984 |
Belongs to: |
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ATP-dependent AMP-binding enzyme family |
Acetoacetyl-CoA synthetase
Mass (kDA):
75.04 kDA
Rat | |
---|---|
Location: | 12q14 |
Sequence: | 12; |
Abundant in male subcutaneous white adipose tissue after weaning. In white adipose tissue, it is preferentially detected in mature adipocytes but not in preadipocytes. The expression in primary preadipocytes increases during the adipocyte differentiation. In brain, it is expressed in the midbrain, pons/medulla, cerebral cortex, hippocampus and cerebellum. The expression in the cerebellum is restricted primarily to glial cells, while in the cerebral cortex, it is restricted to neuronal cells.
PMID: 10682835 by Iwahori A., et al. cDNA-derived amino acid sequence of acetoacetyl-CoA synthetase from rat liver.
PMID: 15992942 by Ohnuki M., et al. Different localization in rat brain of the novel cytosolic ketone body-utilizing enzyme, acetoacetyl-CoA synthetase, as compared to succinyl-CoA:3-oxoacid CoA-transferase.