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- Table of Contents
Facts about 5-azacytidine-induced protein 2.
Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B.
Mouse | |
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Gene Name: | Azi2 |
Uniprot: | Q9QYP6 |
Entrez: | 27215 |
Belongs to: |
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No superfamily |
5-azacytidine induced 2; AZ25-azacytidine-induced protein 2; FLJ21939; NAP15-azacytidine induced gene 2; NF-kappa-B-activating kinase-associated protein 1; TILPNak-associated protein 1
Mass (kDA):
46.091 kDA
Mouse | |
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Location: | 9|9 F3 |
Sequence: | 9; |
Testis, ovary, heart, lung, kidney and brain. Expressed mainly in the spermatocytes or spermatids in the testis.
PMID: 10580148 by Miyagawa J., et al. Isolation of the novel cDNA of a gene of which expression is induced by a demethylating stimulus.
PMID: 17568778 by Ryzhakov G., et al. SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK.