ABCB1 Antibodies

AND ABCB1 ELISA kits, ABCB1 Proteins

Many biological assays use antibodies to detect ABCB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCB1 antibodies...

We validate the specificity of these antibodies to ABCB1 by testing them on tissues known to express ABCB1 positively and negatively. Browse below to find the ABCB1 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ABCB1 Infographic by Boster Bio

All ABCB1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-P-GlycoProtein(MDR) ABCB1 Antibody (Monoclonal, F4)

3 Citations 6 Q&As

Human

IHC, ICC, WB

$370
Cat # MA1060
100 μg/vial

Anti-ABCB1/Mdr1 Antibody

6 Citations

Human

ELISA, IHC, WB

$629
Cat # A00049
100ug

Anti-P Glycoprotein ABCB1 Rabbit Monoclonal Antibody

1 Citations

Human, Mouse, Rat

IHC, WB

$370
Cat # M00049
100 μl

Anti-P Glycoprotein/ABCB1 Antibody Picoband®

6 Citations

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # A00049-1
100 μg/vial

Anti-Hu CD243 Purified ABCB1 Monoclonal Antibody

Human

Flow Cytometry, IP, IHC-P, IHC-F

$299
Cat # M00049-2
0.1 mg

Anti-P-glycoprotein 1 (I583) ABCB1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A00049-2
100ul

Anti-P Glycoprotein/ABCB1 Antibody Picoband®

5 Citations

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A00049-3
100 μg/vial

Anti-P Glycoprotein/ABCB1 Antibody Picoband®

2 Citations

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # A00049-4
100 μg/vial

Anti-P Glycoprotein/ABCB1 Antibody Picoband®

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A00049-5
100 μg/vial

ABCB1 Overview

Facts about ATP-dependent translocase ABCB1.

ABCB1 3D structure. Source: alphafold

ATP-dependent translocase ABCB1 (ABCB1)

Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. .

Gene Information

Human
Gene Name:	ABCB1
Uniprot:	P08183
Entrez:	5243

Family

Belongs to:

ABC transporter superfamily

Alternative Names

ABC20; ABCB1; ABCB1B; ATP-binding cassette sub-family B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; CD243 antigen; CD243; CLCS; colchicin sensitivity; doxorubicin resistance; EC 3.6.3; EC 3.6.3.44; GP170; IBD13; MDR1; MDR1MGC163296; multidrug resistance protein 1; P-glycoprotein 1; P-gp; PGY1; PGY1P-GP

Molecular Weight

Mass (kDA):
141.479 kDA

Genomic Context


Human

Location:	7q21.12
Sequence:	7; NC_000007.14 (87503017..87713323, complement)

Tissue Specificity

Expressed in liver, kidney, small intestine and brain.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Apical cell membrane.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Leukemia
Carcinoma
Mammary Neoplasms
Cholangiocarcinoma
Epilepsy
Myeloid Leukemia
Hiv Infections
Malignant Neoplasm Of Lung
Nervousness
Lung Neoplasms

Myeloid Leukemia, Chronic
Ovarian Neoplasm
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Ovary
Liver Carcinoma
Colonic Neoplasms

Interacting Proteins

LAPTM4B
RNF2

Pathways

Transport
Drug Resistance
Drug Transport
Excretion
Localization
Cell Cycle
Cell Proliferation
Secretion
Methylation
Pathogenesis
Rna Interference
Cell Death
Intestinal Absorption

Cell Growth
Translation
Dna Methylation
Reverse Transcription
Glomerular Filtration
Dna Repair
Gene Silencing

PTMs

Phosphorylation
Methylation
Cleavage
Carboxylation
Acetylation
Demethylation
Glycosylation
Ubiquitination
Reduction

Oxidation
Dephosphorylation
Nitration
Deacetylation
Nitrosylation
Phosphorothioation
Hydroxylation
Bromination
Biotinylation

Research Areas

Cancer
Membrane Trafficking and Chaperones

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCB1

References

PMID: 2876781 by Chen C.-J., et al. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

PMID: 1967175 by Chen C.-J., et al. Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.

21 Publications of Boster ABCB1 Antibodies & ELISA Kits

PubMed ID: 10.7150/thno.13907, P-glycoprotein Mediates Postoperative Peritoneal Adhesion Formation by Enhancing...
PubMed ID: 10.5137/1019-5149.jtn.29819-20.3, Chemoresistance in Malignant Intracranial Tumors: Longer Survival with Negative ...
PubMed ID: 10.3748/wjg.v11.i22.3335, Nude mice multi-drug resistance model of orthotopic transplantation of liver neo...
PubMed ID: 10.1211/jpp.61.06.0016, Glutathione depletion upregulates P‐glycoprotein expression at the blood‐bra...
PubMed ID: 10.1158/1541-7786.MCR-18-1072, Breast Cancer Risk–Associated SNPs in the mTOR Promoter Form De Novo KLF5- and...
PubMed ID: 10.1111/j.1442-2050.2010.01168.x, Various doses of fractioned irradiation modulates multidrug resistance 1 express...
PubMed ID: 10.1038/srep42465, pH-sensitive micelles for the intracellular co-delivery of curcumin and Pluronic...
PubMed ID: 10.1021/ac9026127, Design and Implementation of Electrochemical Cytosensor for Evaluation of Cell S...
PubMed ID: 10.1016/j.phymed.2014.04.029, Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania te...
PubMed ID: 10.1016/j.jns.2016.02.046, Regulation of P-glycoprotein efflux activity by Z-guggulsterone of Commiphora mu...
PubMed ID: 10.1016/j.jep.2013.10.028, The mechanism of the opening of the blood–brain barrier by borneol: A pharmaco...
PubMed ID: 10.1016/j.ijdevneu.2013.10.005, In vitro and in vivo study of dolichyl phosphate on the efflux activity of P-gly...
PubMed ID: 10.1007/s00432-010-0828-5, Expression and significance of hypoxia-inducible factor-1 alpha and MDR1/P-glyco...
PubMed ID: 10.1002/tox.20391, Growth retardation of fetal rats exposed to nicotine in utero: Possible involvem...
PubMed ID: 31467112, Chen Q, Deng X,Hu X,Guan S,He M,Wang Y,Wei B,Zhang J,Zhao H,Yao W,Jin F,Liu Y,Ch...
PubMed ID: 31455288, Sheng X,Li Y,Li Y,Liu W,Lu Z,Zhan J,Xu M,Chen L,Luo X,Cai G,Zhang S.PLOD2 contri...
PubMed ID: -, ACS Appl.Bio Mater.2020,XXXX,XXX,XXX-XXX Publication Date:December 15, 2020 http...
PubMed ID: 31455288, PLOD2 contributes to drug resistance in laryngeal cancer by promoting cancer ste...
PubMed ID: 26824187, A 20(S)-protopanoxadiol derivative overcomes multi-drug resistance by antagonizi...
PubMed ID: 19771531, Gao S, Liu Q, Wang X, Lin B, Zhang S. Med Oncol. 2010 Sep;27(3):960-7. Doi: 10.1...
PubMed ID: 22759348, Wang X, Deng R, Lu Y, Xu Q, Yan M, Ye D, Chen W. Basic Clin Pharmacol Toxicol. 2...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page