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- Table of Contents
Facts about Ankyrin repeat domain-containing protein 13B.
Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane. .
Human | |
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Gene Name: | ANKRD13B |
Uniprot: | Q86YJ7 |
Entrez: | 124930 |
Belongs to: |
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No superfamily |
ankyrin repeat domain 13B; FLJ25555
Mass (kDA):
70.205 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (29589769..29615006) |
Cell membrane. Late endosome. Early endosome. Interaction with EGFR may enhance association with the cell membrane.
PMID: 22298428 by Tanno H., et al. The Ankrd 13 family of UIM-bearing proteins regulates EGF receptor endocytosis from the plasma membrane.