ADAMTS17 Antibodies

AND ADAMTS17 ELISA kits, ADAMTS17 Proteins

Many biological assays use antibodies to detect ADAMTS17, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADAMTS17 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADAMTS17 antibodies...

We validate the specificity of these antibodies to ADAMTS17 by testing them on tissues known to express ADAMTS17 positively and negatively. Browse below to find the ADAMTS17 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: ADAMTS18

ADAMTS17 Infographic by Boster Bio

All ADAMTS17 Products

Product

Figures

Specificity

Applications

Price

Anti-ADAMTS-17 Antibody

Human, Mouse

ELISA, IHC

$380
Cat # A08620
100ul

ADAMTS17 Overview

Facts about A disintegrin and metalloproteinase with thrombospondin motifs 17.

ADAMTS17 3D structure. Source: alphafold

A disintegrin and metalloproteinase with thrombospondin motifs 17 (ADAMTS17)

Gene Information

Human
Gene Name:	ADAMTS17
Uniprot:	Q8TE56
Entrez:	170691

Family

Belongs to:

No superfamily

Alternative Names

A disintegrin and metalloproteinase with thrombospondin motifs 17; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondintype 1 motif, 17; ADAM metallopeptidase with thrombospondin type 1 motif, 17; ADAM-TS 17; ADAM-TS17; ADAMTS-17; EC 3.4.24; EC 3.4.24.-; EC 3.4.24.80; EC 3.4.24.82; FLJ16363; FLJ32769

Molecular Weight

Mass (kDA):
121.127 kDA

Genomic Context


Human

Location:	15q26.3
Sequence:	15; NC_000015.10 (99971437..100342924, complement)

Tissue Specificity

Isoform 1 and isoform 2 are expressed at high levels in the lung, brain, whole eye and retina. Isoform 1 shows a weaker expression in the heart, kidney and skeletal muscle. Isoform 2 shows a weaker expression in the kidney, bone marrow and skeletal muscle. Isoform 1 and isoform 2 are expressed at high levels in the fetal heart, kidney, and whole eye, whereas a weak expression is seen in the fetal liver.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Weill-marchesani Syndrome
Lens Subluxation
Ectopia Lentis
Congenital Ectopia
Luxation Of Lens
Dislocation, Complete
Carcinoma
Dysplasia
Spherophakia
Malignant Neoplasms
Dwarfism
Myopia
Arthritis

Dog Diseases
Prolymphocytic Leukemia
Aneurysm
Melanoma
Malignant Neoplasm Of Breast
Malignant Tumor Of Colon
Geleophysic Dysplasia

Pathways

Coagulation
Cell Migration
Proteolysis
Angiogenesis

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADAMTS17

References

PMID: 11867212 by Cal S., et al. Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.

PMID: 19836009 by Morales J., et al. Homozygous mutations in ADAMTS10 and ADAMTS17 cause lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature.