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- Table of Contents
Facts about Advillin.
Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates.
Human | |
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Gene Name: | AVIL |
Uniprot: | O75366 |
Entrez: | 10677 |
Belongs to: |
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villin/gelsolin family |
ADVIL; advillin; DOC6; FLJ12386; MGC133244; p92DKFZp779O1812
Mass (kDA):
92.027 kDA
Human | |
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Location: | 12q14.1 |
Sequence: | 12; NC_000012.12 (57797376..57818704, complement) |
Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus.
Cytoplasm, cytoskeleton. Cell projection. Cell projection, axon.
PMID: 9664034 by Marks P.W., et al. Advillin (p92): a new member of the gelsolin/villin family of actin regulatory proteins.
PMID: 12034507 by Tumer Z., et al. Genomic structure, chromosome mapping and expression analysis of the human AVIL gene, and its exclusion as a candidate for locus for inflammatory bowel disease at 12q13-14 (IBD2).