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ATG7 Antibodies
AND ATG7 ELISA kits, ATG7 Proteins
Many biological assays use antibodies to detect ATG7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATG7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATG7 antibodies...
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ATG7 Infographic by Boster Bio
All ATG7 Products
Product
Figures
Specificity
Applications
Price
Anti-Apg7/ATG7 Antibody Picoband®
3 Citations 5 Q&As
Human, Mouse, Rat
WB
$370
Cat # PB9479
100 μg/vial
Cat # PB9479
100 μg/vial
Anti-Apg7/ATG7 Antibody Picoband®
2 Citations
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # PA2261
100 μg/vial
Cat # PA2261
100 μg/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00346
100 μl
Cat # M00346
100 μl
Anti-Atg7 (Apg7) Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IF, ICC, WB
$370
Cat # M00346-1
100 μl
Cat # M00346-1
100 μl
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A00346
100 μg/vial
Cat # A00346
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00346-5
100 µg/vial
Cat # A00346-5
100 µg/vial
ATG7 Overview
Facts about Ubiquitin-like modifier-activating enzyme ATG7.
Ubiquitin-like modifier-activating enzyme ATG7 (ATG7)
Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins due to their conjugation with phosphatidylethanolamine. Both systems are necessary for the ATG8 institution to Cvt vesicles and autophagosomes membranes.
Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which leads to modulate adrenal quantity and quality by removing the mitochondria to a basal level to meet cellular energy demands and preventing excess ROS production.
Gene Information
| Human | |
|---|---|
| Gene Name: | ATG7 |
| Uniprot: | O95352 |
| Entrez: | 10533 |
Family
| Belongs to: |
|---|
| ATG7 family |
Alternative Names
APG7 autophagy 7-like (S. cerevisiae); APG7; APG7L; APG7-LIKE; ATG12-activating enzyme E1 ATG7; ATG7 autophagy related 7 homolog (S. cerevisiae); ATG7; Autophagy-related protein 7; DKFZp434N0735; GSA7; hAGP7; ubiquitin activating enzyme E1-like protein; Ubiquitin-activating enzyme E1-like protein; ubiquitin-like modifier-activating enzyme ATG7
Molecular Weight
Mass (kDA):
77.96 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.3 |
| Sequence: | 3; NC_000003.12 (11272348..11564652) |
Tissue Specificity
Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.
Subcellular Localizations
Cytoplasm. Preautophagosomal structure. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
Diseases
- Malignant Neoplasms
- Neoplasms
- Nerve Degeneration
- Carcinoma
- Leukemia
- Neurodegenerative Disorders
- Liver Carcinoma
- Obesity
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Liver Neoplasms
- Inflammation
- Insulin Resistance
Interacting Proteins
- EEF1D
- GABARAP
- GABARAPL1
- GABARAPL2
- IRF2
- MAP1LC3B
- SIRT1
- TP53
Pathways
- Autophagy
- Cell Death
- Conjugation
- Macroautophagy
- Autophagic Cell Death
- Pathogenesis
- Cellular Homeostasis
- Programmed Cell Death
- Transport
- Localization
- Secretion
- Aging
- Cell Cycle
PTMs
- Phosphorylation
- Cleavage
- Ubiquitination
- Acetylation
- Dephosphorylation
- Reduction
- Acylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATG7
bosterbio.com/bosterbio-gene-info-cards/ATG7
References
PMID: 10233149 by Yuan W., et al. Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein.
PMID: 11096062 by Tanida I., et al. The human homolog of Saccharomyces cerevisiae Apg7p is a Protein- activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.
3 Publications of Boster ATG7 Antibodies & ELISA Kits
- PubMed ID: 29552291, Erbin exerts a protective effect against inflammatory bowel disease by suppressi...
- PubMed ID: 27383629, Nrf2 signalling andautophagyare involved in diabetes mellitus-induced defects in...
- PubMed ID: 29113167, Yang J, Sheng S, Yang Q, Li L, Qin S, Yu S, Zhang X. Oncol Lett. 2017 Nov;14(5):...
*More publications can be found for each product on its corresponding product page