ADGRG2 Antibodies

AND ADGRG2 ELISA kits, ADGRG2 Proteins

Many biological assays use antibodies to detect ADGRG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADGRG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADGRG2 antibodies...

We validate the specificity of these antibodies to ADGRG2 by testing them on tissues known to express ADGRG2 positively and negatively. Browse below to find the ADGRG2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADGRG2 Infographic by Boster Bio

All ADGRG2 Products

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Specificity

Applications

Price

Anti-GPR64 ADGRG2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A09959
100ul

GPR64 (ADGRG2) (NM_001079859) Human Over-expression Lysate

Human

$628
Cat # LS010149
100 µg

ADGRG2 Overview

Facts about Adhesion G-protein coupled receptor G2.

ADGRG2 3D structure. Source: alphafold

Adhesion G-protein coupled receptor G2 (ADGRG2)

Orphan receptor. Could be involved in a signal transduction pathway controlling epididymal function and male fertility.

May regulate fluid exchange within epididymis. .

Gene Information

Human
Gene Name:	ADGRG2
Uniprot:	Q8IZP9
Entrez:	10149

Family

Belongs to:

G-protein coupled receptor 2 family

Alternative Names

EDDM6; epididymis-specific (seven transmembrane family); G protein-coupled receptor 64; GPR64; HE6; MGC104454; MGC138738; TM7LN2

Molecular Weight

Mass (kDA):
111.593 kDA

Genomic Context


Human

Location:	Xp22.13
Sequence:	X; NC_000023.11 (18989307..19122956, complement)

Tissue Specificity

Epididymis-specific expression (at protein level). Both subunits are associated with apical membranes of efferent ductule and proximal epididymal duct epithelia. Mainly expressed in the nonciliated principal cells of the proximal excurrent ducts. Specifically over-expressed in Ewing sarcomas but also up-regulated in a number of carcinomas derived from prostate, kidney or lung.

Subcellular Localizations

Apical cell membrane; Multi-pass membrane protein.

Diseases

Male Infertility
Infertility
Tissue Adhesions
Stasis
Neuroblastoma
Arthritis
Schizophrenia

Rheumatoid Arthritis
Degenerative Polyarthritis

Pathways

Spermatogenesis
Cell Adhesion
Gene Silencing
Stem Cell Differentiation
Fertilization
Osteoblast Proliferation
Localization
Sperm Motility
Cell Cycle

Cell Differentiation
Cell Recognition
Pathogenesis
Rna Interference

PTMs

Cleavage

Glycosylation

Gpi Anchoring

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADGRG2

References

PMID: 9150425 by Osterhoff C., et al. Cloning of a human epididymis-specific mRNA, HE6, encoding a novel member of the seven transmembrane-domain receptor superfamily.

PMID: 12420295 by Obermann H., et al. HE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epithelia.