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- Table of Contents
Facts about Rho GTPase-activating protein 31.
Functions as a GTPase-activating protein (GAP) for RAC1 and CDC42.
Required for cell spreading, polarized lamellipodia formation and cell migration..
Mouse | |
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Gene Name: | Arhgap31 |
Uniprot: | A6X8Z5 |
Entrez: | 12549 |
Belongs to: |
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No superfamily |
Cdc42 GTPase-activating protein; CDGAP; KIAA1204; MGC138368; MGC138370; Rho GTPase activating protein 31; rho GTPase-activating protein 31
Mass (kDA):
155.276 kDA
Mouse | |
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Location: | 16|16 B4 |
Sequence: | 16; |
Expressed at highest levels in heart and lung.
PMID: 9786927 by Lamarche-Vane N., et al. CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac.
PMID: 11744688 by Jenna S., et al. The activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectin.