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- Table of Contents
3 Citations 1 Q&As
1 Citations 5 Q&As
Facts about Multidrug resistance-associated protein 4.
Human | |
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Gene Name: | ABCC4 |
Uniprot: | O15439 |
Entrez: | 10257 |
Belongs to: |
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ABC transporter superfamily |
ABCC4; ATP-binding cassette sub-family C member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; EST170205; MOATB; MOAT-BbA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); MOATBcanalicular multispecific organic anion transporter (ABC superfamily); MRP4; MRP4MRP/cMOAT-related ABC transporter; multidrug resistance-associated protein 4; multispecific organic anion transporter B; Multi-specific organic anion transporter B
Mass (kDA):
149.527 kDA
Human | |
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Location: | 13q32.1 |
Sequence: | 13; NC_000013.11 (95019835..95301451, complement) |
Widely expressed, with particularly high levels in prostate, but is barely detectable in liver.
Membrane; Multi-pass membrane protein.
PMID: 9661885 by Lee K., et al. Isolation of MOAT-B, a widely expressed multidrug resistance- associated protein/canalicular multispecific organic anion transporter-related transporter.
PMID: 12105214 by Adachi M., et al. Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing.
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