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ARL2BP Antibodies
AND ARL2BP ELISA kits, ARL2BP Proteins
Many biological assays use antibodies to detect ARL2BP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARL2BP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARL2BP antibodies...
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ARL2BP Infographic by Boster Bio
All ARL2BP Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M07607
100 µl
Cat # M07607
100 µl
Dog, Human, Monkey, Mouse, Rat
IHC, WB
$523
Cat # M07607-1
100 µl
Cat # M07607-1
100 µl
ARL2BP Overview
Facts about ADP-ribosylation factor-like protein 2-binding protein.
ADP-ribosylation factor-like protein 2-binding protein (ARL2BP)
Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ARL2BP |
| Uniprot: | Q9Y2Y0 |
| Entrez: | 23568 |
Family
| Belongs to: |
|---|
| ARL2BP family |
Alternative Names
ADP-ribosylation factor-like 2 binding protein; ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein; BART1binder of Arl Two; BARTArf-like 2 binding protein BART1; Binder of ARF2 protein 1; binder of Arl2
Molecular Weight
Mass (kDA):
18.822 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q13 |
| Sequence: | 16; NC_000016.10 (57245259..57253635) |
Tissue Specificity
Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
Subcellular Localizations
Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. In retina photoreceptor cells, localized in the distal connecting cilia, basal body, ciliary-associated centriole, and
Diseases
- Malignant Neoplasms
- Cell Invasion
- Pancreatic Neoplasm
- Malignant Neoplasm Of Pancreas
- Neoplasm Invasiveness
- Carcinoma, Pancreatic Ductal
- Neoplasm Metastasis
- Metastatic Malignant Neoplasm To The Liver
- Epstein-barr Virus Infections
- Tissue Adhesions
Interacting Proteins
- ARL2
- CFAP20
Pathways
- Transport
- Cytokinesis
- Translation
- Cell Adhesion
- Adenine Nucleotide Transport
- Stress Granule Assembly
- M Phase
- Membrane Fusion
- Cell Cycle Arrest
- Cell Division
- Nucleotide Transport
PTMs
- Ribosylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARL2BP
bosterbio.com/bosterbio-gene-info-cards/ARL2BP
References
PMID: 10488091 by Sharer J.D., et al. The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization.
PMID: 11303027 by Van Valkenburgh H., et al. ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins.