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- Table of Contents
Facts about Ankyrin repeat and LEM domain-containing protein 2.
It is unclear whether it acts as a real PP2A regulatory subunit or if it is involved in recruitment of the PP2A complex. Involved in brain development (PubMed:25259927).
Human | |
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Gene Name: | ANKLE2 |
Uniprot: | Q86XL3 |
Entrez: | 23141 |
Belongs to: |
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ANKLE2 family |
ankyrin repeat and LEM domain containing 2; ankyrin repeat and LEM domain-containing protein 2; FLJ22280; FLJ36132; KIAA0692; LEM domain containing 7; LEMD7
Mass (kDA):
104.114 kDA
Human | |
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Location: | 12q24.33 |
Sequence: | 12; NC_000012.12 (132725503..132761832, complement) |
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
PMID: 22770216 by Asencio C., et al. Coordination of kinase and phosphatase activities by Lem4 enables nuclear envelope reassembly during mitosis.
PMID: 25259927 by Yamamoto S., et al. A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases.