Product Info Summary
SKU: | A08555-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-APC11 ANAPC11 Antibody
SKU/Catalog Number
A08555-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-APC11 ANAPC11 Antibody (Catalog # A08555-1). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
APC11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-APC11 ANAPC11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08555-1)
Host
Rabbit
Contents
APC11 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
APC11 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC11. The immunogen is located within amino acids 70 - 120 of APC11.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ULK4 antibody is human and mouse reactive. Multiple isoforms of ULK4 are known to exist.
Reactive Species
A08555-1 is reactive to ANAPC11 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
9841 MW
Background of Apc11
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08555-1 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
APC11 antibody can be used for detection of APC11 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of APC11 in HeLa cell lysate with APC11 antibody at 1 μg/mL.
Click image to see more details
Immunofluorescence of APC11 in 3T3 cells with APC11 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ANAPC11 (Source: Uniprot.org, NCBI)
Gene Name
ANAPC11
Full Name
Anaphase-promoting complex subunit 11
Weight
9841 MW
Superfamily
RING-box family
Alternative Names
APC11, Apc11p, HSPC214, Anaphase-promoting complex subunit 11, Cyclosome subunit 11, APC11 ANAPC11 APC11, Apc11p, HSPC214 anaphase promoting complex subunit 11 anaphase-promoting complex subunit 11|APC11 anaphase promoting complex subunit 11 homolog|anaphase promoting complex subunit 11 (yeast APC11 homolog)|cyclosome subunit 11|hepatocellular carcinoma-associated RING finger protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ANAPC11, check out the ANAPC11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ANAPC11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-APC11 ANAPC11 Antibody (A08555-1)
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