ALKBH4 Antibodies

AND ALKBH4 ELISA kits, ALKBH4 Proteins

Many biological assays use antibodies to detect ALKBH4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALKBH4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALKBH4 antibodies...

We validate the specificity of these antibodies to ALKBH4 by testing them on tissues known to express ALKBH4 positively and negatively. Browse below to find the ALKBH4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ALKBH4 Infographic by Boster Bio

All ALKBH4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ALKBH4 Antibody

Human, Mouse

IF, ICC, WB

$405
Cat # A09200
100ul

ALKBH4 (NM_017621) Human Over-expression Lysate

Human

$628
Cat # LS054784
100 µg

ALKBH4 Overview

Facts about Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4.

ALKBH4 3D structure. Source: alphafold

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (ALKBH4)

Dioxygenase that mediates demethylation of actin monomethylated at'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.

May be involved in transcription regulation. .

Gene Information

Human
Gene Name:	ALKBH4
Uniprot:	Q9NXW9
Entrez:	54784

Family

Belongs to:

alkB family

Alternative Names

ABH4; ALKBH4 alkB, alkylation repair homolog 4 (E. coli)

Molecular Weight

Mass (kDA):
33.838 kDA

Genomic Context


Human

Location:	7q22.1
Sequence:	7; NC_000007.14 (102456220..102464863, complement)

Tissue Specificity

Widely expressed, with highest expression in pancreas, ovary and spleen.

Subcellular Localizations

Cytoplasm. Nucleus. Nucleus, nucleolus. Midbody. Associates with the contractile ring and midbody.

Interacting Proteins

DTX2
EP300
MLLT3
TRAF4

Pathways

Rna Modification
Regulation Of Gene Expression

PTMs

Decarboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALKBH4

References

PMID: 17979886 by Tsujikawa K., et al. Expression and sub-cellular localization of human ABH family molecules.

PMID: 21166655 by Bjornstad L.G., et al. Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)-and 2-oxoglutarate-dependent decarboxylase ALKBH4.