ADRA2A Antibodies

AND ADRA2A ELISA kits, ADRA2A Proteins

Many biological assays use antibodies to detect ADRA2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADRA2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADRA2A antibodies...

We validate the specificity of these antibodies to ADRA2A by testing them on tissues known to express ADRA2A positively and negatively. Browse below to find the ADRA2A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADRA2A Infographic by Boster Bio

All ADRA2A Products

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Specificity

Applications

Price

Anti-alpha 2a Adrenergic Receptor/ADRA2A Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse, Rat

$370
Cat # PA2197
100 μg/vial

Anti-AR-Alpha 2A (R361) ADRA2A Antibody

Human, Mouse, Rat

IF, IHC

$405
Cat # A00883-2
100ul

Anti-alpha 2a Adrenergic Receptor/ADRA2A Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00883-3
100 μg/vial

ADRA2A Overview

Facts about Alpha-2A adrenergic receptor.

ADRA2A 3D structure. Source: alphafold

Alpha-2A adrenergic receptor (ADRA2A)

Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine.

For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. .

Gene Information

Human
Gene Name:	ADRA2A
Uniprot:	P08913
Entrez:	150

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

a-2A AdrenergicR; ADRA2; ADRA2A; ADRA2Ralpha-2-adrenergic receptor, platelet type; ADRARZNF32; adrenergic, alpha-2A-, receptor; Alpha-2 adrenergic receptor subtype C10; alpha-2A Adrenergic R; alpha-2A adrenergic receptor; alpha2A AdrenergicR; Alpha-2A adrenoceptor; Alpha-2A adrenoreceptor; alpha-2AAR subtype C10; ALPHA2AAR; Alpha-2AAR; ZNF32

Molecular Weight

Mass (kDA):
50.647 kDA

Genomic Context


Human

Location:	10q25.2
Sequence:	10; NC_000010.11 (111077029..111080907)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Attention Deficit Hyperactivity Disorder
Depressive Disorder
Hypertensive Disease
Diabetes Mellitus
Pertussis
Nervousness
Diabetes Mellitus, Non-insulin-dependent
Pain
Malnutrition
Obesity
Heart Failure
Dysequilibrium Syndrome

Mental Disorders
Schizophrenia
Insulin Resistance
Cholangiocarcinoma
Anxiety Disorders
Disease Of Adrenal Medulla
Stress, Psychological

Interacting Proteins

ADRA2C

Pathways

Secretion
Insulin Secretion
Platelet Aggregation
Localization
Reflex
Glucose Homeostasis
Cell Proliferation
Transport
Response To Methylphenidate
Vasoconstriction
Endocytosis
Pathogenesis
Synaptic Transmission

Platelet Activation
Exocytosis
Innervation
Swimming
Cognition
Receptor Transactivation
Gastric Emptying

PTMs

Phosphorylation
Palmitoylation

Cleavage
Acylation

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADRA2A

References

PMID: 2823383 by Kobilka B.K., et al. Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor.

PMID: 2568356 by Fraser C.M., et al. Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation.

1 Publications of Boster ADRA2A Antibodies & ELISA Kits

PubMed ID: 27805929, Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute ...

*More publications can be found for each product on its corresponding product page