This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Activin receptor type-2B.
Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, activin-B/INHBB in addition to inhibin-A/INHA-INHBA).
Human | |
---|---|
Gene Name: | ACVR2B |
Uniprot: | Q13705 |
Entrez: | 93 |
Belongs to: |
---|
protein kinase superfamily |
activin A receptor, type IIB; Activin receptor type IIB; activin receptor type-2B; Activin RIIB; ActivinRIIB; ACTRIIB; ActR-IIB; ACVR2B; EC 2.7.11; EC 2.7.11.30; MGC116908
Mass (kDA):
57.724 kDA
Human | |
---|---|
Location: | 3p22.2 |
Sequence: | 3; NC_000003.12 (38453890..38493142) |
Cell membrane; Single-pass type I membrane protein.
If you're interested in determining the most appropriate Boster Bio antibody for your research, then you've come to the right spot. This article will provide Boster Bio optimization tricks and troubleshooting guides and also a brief overview of Anti-Activin Receptor Type IIB. If you have any questions, feel free to contact our customer service team. We are happy to assist you!
Boster Bio provides immunohistochemistry services and assists in the translation of research assays into diagnostic tests. Boster Bio's troubleshooting guides provide detailed lists of common problems with immunohistochemistry, from weak staining to high background, to the preparation of samples and tips for optimizing them. These guides can also be used to help answer your questions. Boster Bio provides comprehensive troubleshooting tips and identifies the most commonly used techniques and protocols.
Boster Bio's Anti-ACTR IB ACVR2B Antibody is a part of their Picoband (tm) catalog. This antibody reacts with Rats, Mouse, and Human. It has been used successfully in ELISA, immunohistochemistry, and western blot (WB).
ACVR2B belongs to the ActRII family. It is expressed in a variety of tissues which include muscle tissue and heart. Its expression is associated with age and may indicate an increase in cardiovascular aging or heart dysfunction. This marker can be used to track various aspects of heart function and health. However, the most effective use of the ACVR2B marker may not be as clear as those of the ACVR2B gene.
PMID: 8161782 by Hilden K., et al. Expression of type II activin receptor genes during differentiation of human K562 cells and cDNA cloning of the human type IIB activin receptor.
PMID: 9621519 by Ishikawa S., et al. Genomic organization and mapping of the human activin receptor type IIB (hActR-IIB) gene.