AP1B1 Antibodies

AND AP1B1 ELISA kits, AP1B1 Proteins

Many biological assays use antibodies to detect AP1B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP1B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP1B1 antibodies...

We validate the specificity of these antibodies to AP1B1 by testing them on tissues known to express AP1B1 positively and negatively. Browse below to find the AP1B1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP1B1 Infographic by Boster Bio

All AP1B1 Products

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Specificity

Applications

Price

AP1B1 (NM_001127) Human Recombinant Protein

$813
Cat # PROTQ10567
20 µg

AP1B1 (NM_001127) Human Over-expression Lysate

Human

$960
Cat # LS000162
100 µg

AP1B1 Overview

Facts about AP-1 complex subunit beta-1.

AP1B1 3D structure. Source: alphafold

AP-1 complex subunit beta-1 (AP1B1)

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Gene Information

Human
Gene Name:	AP1B1
Uniprot:	Q10567
Entrez:	162

Family

Belongs to:

adaptor complexes large subunit family

Alternative Names

Adapter-Related Protein Complex 1 Subunit Beta-1; Adaptor Protein Complex AP-1 Subunit Beta-1; Adaptor-Related Protein Complex 1, Beta 1 Subunit; AP-1 Complex Subunit Beta-1; AP105A; AP1B1 ; BAM22; beta-1-adaptin; beta1-adaptin; Beta-Adaptin 1; beta-prime-adaptin; CLAPB2; Clathrin Assembly Protein Complex 1 Beta Large Chain; Golgi Adaptor HA1/AP1 Adaptin Beta Subunit; Plasma Membrane Adaptor HA2/AP2 Adaptor Beta Subunit

Molecular Weight

Mass (kDA):
104.637 kDA

Genomic Context


Human

Location:	22q12.2
Sequence:	22; NC_000022.11 (29327680..29388583, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Diseases

Meningioma
Neoplasms
Meningeal Neoplasms
Tetanus
Hepatitis
Hepatitis C
Neurofibromatoses
Opitz-g Syndrome, Type 2
Neurofibromatosis 2
Inflammation

Crohn Disease
Immune System Diseases
Viremia
Colitis
Liver Regeneration Disorder

Interacting Proteins

Ap1m1

Pathways

Transport
Localization
Intracellular Transport
Cell Growth
Endocytosis
Membrane Fusion
Protein Transport

Secretion
Cell Maturation

PTMs

Cleavage

Research Areas

Membrane Vesicle Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP1B1

References

PMID: 7987321 by Peyrard M., et al. Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene.

PMID: 8812422 by Peyrard M., et al. Structure of the promoter and genomic organization of the human beta'-adaptin gene (BAM22) from chromosome 22q12.