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- Table of Contents
Facts about A disintegrin and metalloproteinase with thrombospondin motifs 20.
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Human | |
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Gene Name: | ADAMTS20 |
Uniprot: | P59510 |
Entrez: | 80070 |
Belongs to: |
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No superfamily |
A disintegrin and metalloproteinase with thrombospondin motifs 20
Mass (kDA):
214.721 kDA
Human | |
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Location: | 12q12 |
Sequence: | 12; NC_000012.12 (43352843..43552203, complement) |
Very sparingly expressed, although is detected at low levels in testis, prostate, ovary, heart, placenta, lung and pancreas. Overexpressed in several brain, colon and breast carcinomas.
Secreted, extracellular space, extracellular matrix.
PMID: 12514189 by Somerville R.P., et al. Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1.
PMID: 12562771 by Llamazares M., et al. Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain.