AP5S1 Antibodies

AND AP5S1 ELISA kits, AP5S1 Proteins

Many biological assays use antibodies to detect AP5S1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP5S1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP5S1 antibodies...

We validate the specificity of these antibodies to AP5S1 by testing them on tissues known to express AP5S1 positively and negatively. Browse below to find the AP5S1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP5S1 Infographic by Boster Bio

All AP5S1 Products

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Product

Figures

Specificity

Applications

Price

AP5S1 (NM_018347) Human Recombinant Protein

$1062
Cat # PROTQ9NUS5
20 µg

AP5S1 (NM_018347) Human Over-expression Lysate

Human

$628
Cat # LS055317
100 µg

AP5S1 Overview

Facts about AP-5 complex subunit sigma-1.

AP5S1 3D structure. Source: alphafold

AP-5 complex subunit sigma-1 (AP5S1)

As part of AP-5, a likely fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862, it is required for efficient homologous recombination DNA double-strand break repair.

Gene Information

Human
Gene Name:	AP5S1
Uniprot:	Q9NUS5
Entrez:	55317

Family

Belongs to:

No superfamily

Alternative Names

adaptor-related protein complex 5, sigma 1 subunit; C20orf29; chromosome 20 open reading frame 29; FLJ11168; hypothetical protein LOC55317

Molecular Weight

Mass (kDA):
22.522 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (3820524..3828838)

Subcellular Localizations

Cytoplasm, cytosol. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP5S1

References

PMID: 20613862 by Slabicki M., et al. A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia.

PMID: 22022230 by Hirst J., et al. The fifth adaptor protein complex.