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- Table of Contents
Facts about Amyloid-beta A4 precursor protein-binding family A member 1.
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Human | |
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Gene Name: | APBA1 |
Uniprot: | Q02410 |
Entrez: | 320 |
Belongs to: |
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No superfamily |
Adapter protein X11alpha; amyloid beta (A4) precursor protein-binding, family A, member 1; amyloid beta A4 precursor protein-binding family A member 1; D9S411Eadaptor protein X11alpha; LIN10; mint-1; MINT1amyloid beta (A4) precursor protein-binding, family A, member 1 (X11); Neuronal Munc18-1-interacting protein 1; Neuron-specific X11 protein; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; UROP11; X11A; X11X11ALPHA
Mass (kDA):
92.865 kDA
Human | |
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Location: | 9q21.12 |
Sequence: | 9; NC_000009.12 (69427532..69673012, complement) |
Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen.
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Only about 5% of the protein is located in the nucleus.; [Isoform 2]: Golgi apparatus.
PMID: 9395480 by Okamoto M., et al. Mints, Munc18-interacting proteins in synaptic vesicle exocytosis.
PMID: 9614075 by Borg J.-P., et al. The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion.