ADARB1 Antibodies

AND ADARB1 ELISA kits, ADARB1 Proteins

Many biological assays use antibodies to detect ADARB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADARB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADARB1 antibodies...

We validate the specificity of these antibodies to ADARB1 by testing them on tissues known to express ADARB1 positively and negatively. Browse below to find the ADARB1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ADARB1 Infographic by Boster Bio

All ADARB1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ADARB1/Red1 Antibody

4 Q&As

Human, Mouse, Rat

$360
Cat # A01810
100 µl

ADARB1 Colorimetric Cell-Based ELISA

Human, Mouse, Rat

ELISA

$480
Cat # EKC1764
1 kit, containing one 96-well plate and all necessary reagents

Anti-ADAR2 (R510) ADARB1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A01810-1
100ul

Anti-RED1/ADARB1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A01810-2
100 μg/vial

RED1 (ADARB1) (NM_001112) Human Over-expression Lysate

Human

$628
Cat # LS000104
100 µg

ADARB1 Overview

Facts about Double-stranded RNA-specific editase 1.

ADARB1 3D structure. Source: alphafold

Double-stranded RNA-specific editase 1 (ADARB1)

Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may influence gene expression and function in a variety of ways that have mRNA translation by altering codons and therefore the amino acid sequence of proteins; pre-mRNA splicing by changing splice site recognition sequences; RNA stability by altering sequences involved in nuclease recognition; genetic stability in the event of RNA virus genomes by altering sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions.

Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at particular sites (site-specific editing). Its cellular RNA substrates include: bladder cancer- associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2 and GRIK2) and serotonin (HTR2C), GABA receptor (GABRA3) and potassium voltage-gated channel (KCNA1).

Gene Information

Human
Gene Name:	ADARB1
Uniprot:	P78563
Entrez:	104

Family

Belongs to:

No superfamily

Alternative Names

ADAR2a; ADAR2ADAR2g; ADAR2a-L1; ADAR2a-L2; ADAR2a-L3; ADAR2b; ADAR2c; adenosine deaminase, RNA-specific, B1; double-stranded RNA-specific editase 1; DRABA2; DRADA2hRED1; EC 3.5; human dsRNA adenosine deaminase DRADA2; human dsRNA adenosine deaminase DRADA2b, EC 3.510adenosine deaminase, RNA-specific, B1 (homolog of rat RED1); RED1 homolog; RED1ADAR2d; RNA editase; RNA editing deaminase 1; RNA-editing deaminase 1; RNA-editing enzyme 1; RNA-specific, B1 (RED1 homolog rat)

Molecular Weight

Mass (kDA):
80.763 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (45074578..45226563)

Tissue Specificity

Highly expressed in brain and heart and at lower levels in placenta. Fair expression in lung, liver and kidney. Detected in brain, heart, kidney, lung and liver (at protein level). Isoform 5 is high expressed in hippocampus and colon. Isoform 5 is expressed in pediatric astrocytomas and the protein has a decreased RNA-editing activity. The decrease in RNA editing correlates with the grade of malignancy of the tumors, with the high grade tumors showing lower editing is seen.