AP1S2 Antibodies

AND AP1S2 ELISA kits, AP1S2 Proteins

Many biological assays use antibodies to detect AP1S2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP1S2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP1S2 antibodies...

We validate the specificity of these antibodies to AP1S2 by testing them on tissues known to express AP1S2 positively and negatively. Browse below to find the AP1S2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP1S2 Infographic by Boster Bio

All AP1S2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human AP1S2 Recombinant Protein

SDS-PAGE

$265
Cat # PROTP56377
Starting from 10ug

AP1S2 (NM_003916) Human Over-expression Lysate

Human

$628
Cat # LS008905
100 µg

AP1S2 Overview

Facts about AP-1 complex subunit sigma-2.

AP1S2 3D structure. Source: alphafold

AP-1 complex subunit sigma-2 (AP1S2)

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Gene Information

Human
Gene Name:	AP1S2
Uniprot:	P56377
Entrez:	8905

Family

Belongs to:

adaptor complexes small subunit family

Alternative Names

adaptor-related protein complex 1, sigma 2 subunit; MGC:1902; SIGMA1B; X-linked 59

Molecular Weight

Mass (kDA):
18.615 kDA

Genomic Context


Human

Location:	Xp22.2
Sequence:	X; NC_000023.11 (15825806..15854966, complement)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.

Diseases

Muscle Hypotonia
Benign Neoplasm
Optic Atrophies, Hereditary
Genetic Diseases, X-linked
Developmental Delay (disorder)
Uterine Neoplasms
Hydrocephalus
Endoplasmic Reticulum Stress
Congenital Anomaly Of Face
Autistic Disorder

Speech Delay
Neoplasms
Fibroid Tumor
Inflammation
Calcinosis

Pathways

Methylation
Dna Hypomethylation
Dna Methylation
Pathogenesis
Localization

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP1S2

References

PMID: 9733768 by Takatsu H., et al. Identification and characterization of novel clathrin adaptor-related proteins.

PMID: 15471854 by Kinlough C.L., et al. MUC1 membrane trafficking is modulated by multiple interactions.