Product Info Summary
SKU: | A07968 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-RHG17 ARHGAP17 Antibody
SKU/Catalog Number
A07968
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-RHG17 ARHGAP17 Antibody (Catalog # A07968). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-RHG17 ARHGAP17 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07968)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of humanRHG17.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A07968 is reactive to ARHGAP17 in Human, Mouse, Rat
Reconstitution
Calculated molecular weight
95437 MW
Background of ARHGAP17
Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. Specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere. Participates in the Ca2+-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
Richnau N., J. Biol. Chem. 276:35060-35070(2001).
Ota T., Nat. Genet. 36:40-45(2004).
The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07968 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from LOVO cells, using RHG17 antibody A07968.
Protein Target Info & Infographic
Gene/Protein Information For ARHGAP17 (Source: Uniprot.org, NCBI)
Gene Name
ARHGAP17
Full Name
Rho GTPase-activating protein 17
Weight
95437 MW
Alternative Names
Rho GTPase-activating protein 17;Rho-type GTPase-activating protein 17;RhoGAP interacting with CIP4 homologs protein 1;RICH-1;ARHGAP17;RICH1;MSTP066, MSTP110; ARHGAP17 MST066, MST110, MSTP038, MSTP066, MSTP110, NADRIN, PP367, PP4534, RICH-1, RICH1, WBP15 Rho GTPase activating protein 17 rho GTPase-activating protein 17|RhoGAP interacting with CIP4 homologs 1|neuron-associated developmentally regulated protein|rho-type GTPase-activating protein 17
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ARHGAP17, check out the ARHGAP17 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ARHGAP17: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RHG17 ARHGAP17 Antibody (A07968)
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No publications found for A07968
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Customer Reviews
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Customer Q&As
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6 Customer Q&As for Anti-RHG17 ARHGAP17 Antibody
Question
Do you have a BSA free version of anti-RHG17 antibody A07968 available?
Verified Customer
Verified customer
Asked: 2019-12-24
Answer
We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-RHG17 antibody A07968 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2019-12-24
Question
Is this A07968 anti-RHG17 antibody reactive to the isotypes of ARHGAP17?
B. Miller
Verified customer
Asked: 2019-08-29
Answer
The immunogen of A07968 anti-RHG17 antibody is Synthesized peptide derived from internal of humanRHG17. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?
Boster Scientific Support
Answered: 2019-08-29
Question
Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for aorta using anti-RHG17 antibody A07968. Let me know if you need anything else.
N. Anderson
Verified customer
Asked: 2019-07-09
Answer
We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2019-07-09
Question
We are currently using anti-RHG17 antibody A07968 for rat tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it true that the antibody can work on feline tissues as well?
Verified Customer
Verified customer
Asked: 2019-03-22
Answer
The anti-RHG17 antibody (A07968) has not been validated for cross reactivity specifically with feline tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-03-22
Question
I am interested in to test anti-RHG17 antibody A07968 on rat aorta for research purposes, then I may be interested in using anti-RHG17 antibody A07968 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?
B. Mitchell
Verified customer
Asked: 2017-12-19
Answer
The products we sell, including anti-RHG17 antibody A07968, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.
Boster Scientific Support
Answered: 2017-12-19
Question
I see that the anti-RHG17 antibody A07968 works with WB, what is the protocol used to produce the result images on the product page?
C. Wu
Verified customer
Asked: 2013-03-11
Answer
You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2013-03-11