Product Info Summary
SKU: | A07801 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-AJAP1 Antibody
View all Shrew-1/AJAP1 Antibodies
SKU/Catalog Number
A07801
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-AJAP1 Antibody (Catalog # A07801). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
AJAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-AJAP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07801)
Host
Rabbit
Contents
AJAP1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
AJAP1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human AJAP1. The immunogen is located within amino acids 290 - 340 of AJAP1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
AJAP1 antibody is human, mouse and rat reactive.
Reactive Species
A07801 is reactive to AJAP1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
44536 MW
Background of Shrew-1/AJAP1
The Adherens Junction Associated Protein 1 (AJAP1) plays a key role in cell adhesion and cell migration (1). It is a transmembrane protein found on the basolateral surface of epithelium and expressed by multiple types of epithelium (1,2). AJAP1 interacts with E-Cadherin and appears to promote the internalization of E-Cadherin upon growth factor stimulation (3). This facilitates the dissolution of adherens junctions with an increase in cell motility (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A07801 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
AJAP1 antibody can be used for detection of AJAP1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in rat samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of AJAP1 in rat liver tissue lysate with AJAP1 antibody at 1 μg/ml.
Click image to see more details
Immunocytochemistry of AJAP1 in K562 cells with AJAP1 at 2.5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For AJAP1 (Source: Uniprot.org, NCBI)
Gene Name
AJAP1
Full Name
Adherens junction-associated protein 1
Weight
44536 MW
Alternative Names
Adherens junctions associated protein 1, Membrane protein shrew-1, MOT8, SHREW1 AJAP1 MOT8, SHREW-1, SHREW1 adherens junctions associated protein 1 adherens junction-associated protein 1|membrane protein shrew-1|transmembrane protein SHREW1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AJAP1, check out the AJAP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AJAP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-AJAP1 Antibody (A07801)
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