AP3B2 Antibodies

AND AP3B2 ELISA kits, AP3B2 Proteins

Many biological assays use antibodies to detect AP3B2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP3B2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP3B2 antibodies...

We validate the specificity of these antibodies to AP3B2 by testing them on tissues known to express AP3B2 positively and negatively. Browse below to find the AP3B2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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AP3B2 Infographic by Boster Bio

All AP3B2 Products

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Specificity

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Price

Anti-AP-3 complex subunit beta-2 AP3B2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A09539
0.1 mg

AP3B2 (NM_004644) Human Over-expression Lysate

Human

$628
Cat # LS008120
100 µg

AP3B2 Overview

Facts about AP-3 complex subunit beta-2.

AP3B2 3D structure. Source: alphafold

AP-3 complex subunit beta-2 (AP3B2)

Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is needed to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Gene Information

Human
Gene Name:	AP3B2
Uniprot:	Q13367
Entrez:	8120

Family

Belongs to:

adaptor complexes large subunit family

Alternative Names

Adapter-related protein complex 3 subunit beta-2; Adaptor protein complex AP-3 subunit beta-2; adaptor-related protein complex 3, beta 2 subunit; beta-3B-adaptin; Clathrin assembly protein complex 3 beta-2 large chain; DKFZp686D17136; NAPTBAP-3 complex subunit beta-2; Neuronal adaptin-like protein, beta-subunit; Neuron-specific vesicle coat protein beta-NAP

Molecular Weight

Mass (kDA):
119.059 kDA

Genomic Context


Human

Location:	15q25.2
Sequence:	15; NC_000015.10 (82659281..82709908, complement)

Tissue Specificity

Expression is specific to nervous system. Expressed in nerve terminal and cell body, and is associated with nerve-terminal vesicles. Expression seen in Purkinje cells, cortical neurons, neuroectodermal tumors and graded in cerebral cortex (deeper layers exhibit stronger expression).

Subcellular Localizations

Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.