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- Table of Contents
Facts about AP-4 complex subunit beta-1.
They control the vesicular transport of proteins in different trafficking pathways (PubMed:10066790, PubMed:10436028). AP-4 forms a non clathrin- associated coating on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins in the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Human | |
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Gene Name: | AP4B1 |
Uniprot: | Q9Y6B7 |
Entrez: | 10717 |
Belongs to: |
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adaptor complexes large subunit family |
Adapter-related protein complex 4 subunit beta-1; adaptor-related protein complex 4, beta 1 subunit; AP-4 adapter complex subunit beta; AP-4 complex subunit beta-1; beta 4 subunit of AP-4; Beta subunit of AP-4; BETA-4; beta4-adaptin
Mass (kDA):
83.26 kDA
Human | |
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Location: | 1p13.2 |
Sequence: | 1; NC_000001.11 (113894194..113905067, complement) |
Widely expressed.
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
PMID: 10066790 by Dell'Angelica E.C., et al. AP-4, a novel protein complex related to clathrin adaptors.
PMID: 10436028 by Hirst J., et al. Characterization of a fourth adaptor-related protein complex.