ALG6 Antibodies

AND ALG6 ELISA kits, ALG6 Proteins

Many biological assays use antibodies to detect ALG6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ALG6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ALG6 antibodies...

We validate the specificity of these antibodies to ALG6 by testing them on tissues known to express ALG6 positively and negatively. Browse below to find the ALG6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: GPR132

ALG6 Infographic by Boster Bio

All ALG6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ALG6 Antibody

4 Q&As

Human

ELISA, IHC, WB

$629
Cat # A07747
100uL

ALG6 (NM_013339) Human Over-expression Lysate

Human

$628
Cat # LS029929
100 µg

ALG6 Overview

Facts about Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase.

ALG6 3D structure. Source: alphafold

Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG6)

Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) on the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.

Gene Information

Human
Gene Name:	ALG6
Uniprot:	Q9Y672
Entrez:	29929

Family

Belongs to:

ALG6/ALG8 glucosyltransferase family

Alternative Names

alpha-1,3-glucosyltransferase); asparagine-linked glycosylation 6 homolog (S. cerevisiae; asparagine-linked glycosylation 6 homolog (yeast; asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S.cerevisiae); Asparagine-linked glycosylation protein 6 homolog; CDG1C; dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase; dolichyl-P-Glc:Man9GlcNAc2-PP-dolichylglucosyltransferase; EC 2.4.1; EC 2.4.1.-; Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase

Molecular Weight

Mass (kDA):
58.121 kDA

Genomic Context


Human

Location:	1p31.3
Sequence:	1; NC_000001.11 (63367627..63438553)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Congenital Disorders
Congenital Disorders Of Glycosylation
Strabismus
Pseudotumor Cerebri
Virilism
Muscle Hypotonia
Congenital Cerebellar Hypoplasia
Limb Deformities, Congenital
Retinal Degeneration
Inborn Errors Of Metabolism
Ataxia
De Novo Mutation

Intestinal Diseases
Congenital Exomphalos
Endoplasmic Reticulum Stress
Dysplasia
Pseudotumor
Congenital Omphalocele

Pathways

Glycosylation
Protein Glycosylation
Transport
Translation
Udp-glucose Transport

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ALG6

References

PMID: 10359825 by Imbach T., et al. A mutation in the human ortholog of the Saccharomyces cerevisiae ALG6 gene causes carbohydrate-deficient glycoprotein syndrome type-Ic.

PMID: 11106564 by Westphal V., et al. Reduced heparan sulfate accumulation in enterocytes contributes to protein-losing enteropathy in a congenital disorder of glycosylation.